GoKawiilResearchers develop drugs that mimic exercise's effects in mice and early human trials
Pharmacologist Thomas Burris and colleagues created a compound that activates a muscle receptor normally boosted by exercise, producing mice with greater endurance and possible cognitive and heart-failure benefits; Burris founded Pelagos to pursue a clinical trial. Separately, biotech firm Cambrian Bio reported in June that its drug ATX-304 raised metabolism and cut liver and belly fat in obese, prediabetic patients by activating an energy-sensing cellular switch.