GoKawiilScientists study 'super-agers' and rare ApoE gene variants to find Alzheimer's clues
Geneticist Henne Holstege began a 2013 project studying people who remain resistant to dementia despite age or genetic risk factors, after years of failed funding attempts. Researchers have since identified several rare gene variants, including some affecting the ApoE protein, that appear to protect the brain against the toxic proteins linked to Alzheimer's disease.