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Hippocampus

2 GoKawiil briefs on this topic

Study finds aging hippocampus blends separate memories rather than erasing them

Researchers scanning brains of adults aged 18 to 74 found that memory accuracy for face-object and face-scene pairings dropped sharply after young adulthood, with middle-aged and older participants performing similarly rather than declining gradually. In older adults, the same hippocampal activity patterns that supported accurate recall in younger people were instead linked to cross-category errors, such as confusing a scene with an object. The study, published in Cerebral Cortex, found that brain shrinkage and attention differences did not fully explain this shift.

Single-cell study links depression to impaired hippocampal neurogenesis

Researchers analyzed nearly half a million brain cells from tissue of 30 deceased individuals, creating a detailed cellular map of the adult hippocampus. The study, published in Nature Medicine, found that people who had depression showed disrupted production of new neurons compared with those without the disorder.