GoKawiilMachine perfusion found to biologically de-age donor livers before transplant
Researchers led by Adrien Longchamp and Bohan Poganik used aging clocks to show that livers pumped with oxygen and nutrients at 34 degrees on perfusion machines became biologically younger, with roughly a 30% difference compared to non-perfused organs after adjusting for chronological age. The effect persisted even after transplantation, though biological age rose in all livers once implanted, likely due to surgical stress.