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Lymph Nodes

2 GoKawiil briefs on this topic

PLA2G2D enzyme in lymph nodes found to suppress anti-tumor immune response

Researchers analyzed tumor-draining lymph nodes from melanoma and non-small cell lung cancer patients, comparing those with early disease recurrence to those without, using tissue collected during routine diagnostic procedures at Erasmus MC. The study identifies the enzyme PLA2G2D as a regulator within these lymph nodes that influences how effectively the immune system mounts a response against tumors.

Study Links Alzheimer's Brain Damage to Immune Cells in Lymph Nodes

Researchers have identified immune cells located in the lymph nodes, outside the brain, as a significant driver of the neurological damage associated with Alzheimer's disease. The findings suggest that the disease's roots may extend beyond the brain itself into the body's broader immune system.