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Lymphoma

2 GoKawiil briefs on this topic

Genmab Shares Rise Following Positive Blood-Cancer Treatment Data

Genmab announced that its collaboration with AbbVie demonstrated that their drug Epkinly increased survival time for patients with a prevalent form of lymphoma. The results were presented in a recent study, prompting a surge in Genmab's stock price. The findings suggest potential for expanded use of the medication in blood cancer therapies.

Study identifies MLLT1 and MLLT3 as factors that focus AID onto specific gene loci

Researchers report that the histone-reader proteins MLLT1 and MLLT3 help concentrate the enzyme AID at particular genomic locations in B cells. This targeting mechanism appears to explain how AID achieves locus specificity during processes such as somatic hypermutation, rather than acting broadly across the genome.