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Massachusetts General Hospital

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eGenesis Pig Kidney Functions 285 Days in Massachusetts General Patient

A woman who received a gene-edited pig kidney transplant at Massachusetts General Hospital last November has now gone 285 days without needing dialysis, breaking the previous 271-day record set by Tim Andrews. The kidney was engineered by eGenesis using Crispr gene editing to remove pig genes that trigger immune rejection and add human genes, and she is the fifth patient to receive one of the company's kidneys.

Scientists still can't fully explain how SSRIs work despite decades of use

Researchers acknowledge that although SSRIs remain among the world's most widely prescribed medications, the precise biological mechanism by which they relieve depression is still not understood. The debate intensified after US Health Secretary Robert F. Kennedy Jr. claimed the drugs are overprescribed and carry withdrawal risks comparable to heroin, sparking pushback from some clinicians while others said he raised a legitimate concern.