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Mllt3

2 GoKawiil briefs on this topic

Nature publishes author correction for MLLT1/MLLT3 AID study

Nature has issued an author correction to a previously published paper describing how histone readers MLLT1 and MLLT3 concentrate AID to confer locus specificity. The notice itself provides no details on the nature of the correction, as the page displays only a generic access message without the corrected content.

Study identifies MLLT1 and MLLT3 as factors that focus AID onto specific gene loci

Researchers report that the histone-reader proteins MLLT1 and MLLT3 help concentrate the enzyme AID at particular genomic locations in B cells. This targeting mechanism appears to explain how AID achieves locus specificity during processes such as somatic hypermutation, rather than acting broadly across the genome.