GoKawiilComplement factor H found inside retinal neurons shields them from MS-related inflammation
Researchers analyzed post-mortem retinal and brain tissue from multiple sclerosis patients and healthy controls, using single-nucleus RNA sequencing, immunohistochemistry and other molecular techniques. They identified an intracellular form of complement factor H within neurons that appears to protect these cells from damage during central nervous system inflammation, a mechanism distinct from the protein's known extracellular immune role.