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Researchers highlight six emerging drug-delivery technologies

A Nature feature surveys six novel approaches under development for delivering drugs more precisely and effectively, ranging from advanced nanoparticle carriers to devices designed to target specific tissues. These innovations aim to overcome longstanding challenges such as poor bioavailability, degradation before reaching target sites, and off-target side effects.

Researchers engineer bacteria as targeted cancer treatment delivery agents

Scientists are developing genetically modified bacteria designed to seek out and treat tumors from within the body. The approach relies on engineering microbes to recognize cancerous tissue and deliver therapeutic effects directly at the tumor site.

William Thomson's Legacy: The Man Behind the Kelvin Scale

A Nature retrospective highlights the scientific career of William Thomson, later Lord Kelvin, noting that his contributions extended well beyond the temperature scale that bears his name. The piece surveys his broader body of work in physics and engineering during the 19th century.

Nature calls for restrictions on prediction markets betting on clinical trial results

An editorial in Nature argues that prediction markets allowing wagers on the outcomes of clinical trials pose risks to research integrity and public trust in science. It calls for limits on such betting activity to prevent interference with ongoing trials.

Nepal flood disaster highlights danger of compounding climate hazards

A recent catastrophic flood event in Nepal illustrates how multiple climate-related hazards can combine to produce disasters far more severe than any single risk factor would suggest. Nature's commentary uses the event to argue that scientists and policymakers have been underestimating the danger posed by such compound risks.

Nature commentary urges patient-centered oversight of medical AI systems

A commentary published in Nature argues that governance frameworks for AI in healthcare should place patients, not just clinicians or regulators, at the center of decision-making. The piece calls for structures that give patients meaningful input into how AI tools are developed, deployed and monitored in clinical settings.

Study identifies hidden role for cell-cycle gatekeeper protein in breast cancer

Researchers examined a regulatory protein that controls the cell cycle and found it has an additional, previously unrecognized function tied to breast cancer development. The finding, published via Nature, points to a more complex biological role for this gatekeeper than earlier assumed.

Nature.com re-surfaces 2000 essay 'Catching Crumbs from the Table' amid browser compatibility notice

A visitor to nature.com attempting to access an archived piece titled 'Catching Crumbs from the Table' from 2000 instead encountered a generic browser-compatibility notice rather than the article's actual content. The page indicated the site was being displayed without full styling or JavaScript because of the outdated browser being used, leaving the substance of the original 2000 piece inaccessible in this instance.

Optical clocks across four countries synchronized in landmark comparison

Scientists linked ultra-precise optical atomic clocks located in four different nations and successfully compared their timekeeping with extremely high accuracy. The experiment demonstrated that these clocks, which are far more precise than the cesium clocks defining current international time standards, can be reliably synced across long distances.

Researchers bury 1,000 cotton underpants to gauge global soil health

Scientists used a citizen-science method of burying cotton underwear in soil for several months as a low-cost way to assess microbial activity, since healthier soil decomposes cotton fabric faster. Volunteers around the world dug up roughly 1,000 pairs and reported how much material had degraded, generating a broad dataset on soil condition.

Study finds ancient Egyptian mummy portraits used human hair from diverse, non-local sources

Researchers analyzed body parts, likely hair, incorporated into ancient Egyptian artworks and traced their origin to sources that differ from long-held assumptions about local production. The findings suggest a more complex supply chain behind these artifacts than previously believed.

Study identifies biomarkers linked to better outcomes from perioperative immunotherapy in lung cancer

Researchers report findings on biological markers that correlate with improved patient outcomes when immune-based therapies are used before and after surgery for lung cancer. The publication, appearing on Nature's platform, outlines how certain biomarkers may help predict which patients respond best to this perioperative treatment approach.