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Ovarian Aging

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Study finds postmenopausal ovaries remain biologically active, linked to cancer markers

Researchers at Northwestern University and the Buck Institute analyzed ovarian tissue from 28 women using proteomics and mass spectrometry, finding hundreds of proteins continue to change long after menopause. The tissue showed ongoing remodeling, rising inflammation, and molecular signatures overlapping with those seen in ovarian cancer. The findings were published October 14 in Aging Cell.