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Peptide Nanofibrils

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Researchers design peptide nanofibrils with sequence-encoded hexagonal channel structures

A research team synthesized a series of short peptides—including DILT1 through DILT5 and related sequences—using automated solid-phase peptide synthesis to create multichannel nanofibrils. The peptides self-assemble into structures whose lattice geometry is dictated by their specific amino acid sequences, producing hexagonal channel arrangements at the nanoscale.