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Alzheimer's brains yield over 1,000 unrecognized 'microproteins'

Researchers analyzed human brain tissue samples from people with and without Alzheimer's disease and identified more than 1,000 microproteins that had previously gone undetected. Dozens of these small proteins showed different expression levels in Alzheimer's-affected brains compared with healthy ones. Separately, a mouse study found that immune cells activated by gut infections can travel to the brain's protective membrane and remain there as a lasting defensive memory.

Modders find workarounds to speed up Nvidia's DLSS 5 neural rendering

Independent testers have built two unofficial fixes for DLSS 5's steep performance cost, which Nvidia's own benchmarks showed can nearly halve frame rates on RTX 50-series cards. One method, a ReShade add-on called Neural Upstream, reorders the pipeline so the neural pass runs on the smaller pre-upscaled image rather than the full output frame, cutting its processing load by roughly two-thirds of the pixel count. Early tests on an RTX 4080 in Assassin's Creed Shadows show the neural rendering overhead dropping from about 32 FPS to 13 FPS lost, a 61% improvement, with similar gains reported in other titles.

Buyer's guide: what to check before buying a portable Apple CarPlay screen

Portable CarPlay screens typically cost between $50 and $150, offering a cheaper alternative to buying a new car with built-in infotainment. Buyers should weigh screen size (6 to 11 inches), resolution (ideally at least 1280x720), audio output options like Bluetooth, AUX or FM, and whether the unit supports wireless CarPlay rather than requiring a cable.

Qualcomm details next Snapdragon Elite GPU with Adreno Matrix Cores for AI upscaling

Qualcomm has shared new details on the GPU inside its upcoming flagship Snapdragon chip, revealing three new Adreno Matrix Cores designed to run AI workloads with lower latency and better power efficiency. These cores power a new feature called Adreno Neural Fusion, which handles frame generation and AI-based upscaling, promising fewer visual artifacts, more stable performance, and up to 40% lower power use than Qualcomm's earlier solution.

Dell unveils 14S laptop as budget rival to Apple's MacBook Neo

Dell has announced the 14S, a mainstream 14-inch laptop offered in four colors with a 61.2 Whr battery for all-day use. It comes with up to an Intel Core 7 processor, choice of FHD or 2.8K displays, up to 16GB of RAM, up to 1TB of storage, and weighs just over 2.5 pounds. Pricing hasn't been announced yet; Dell says details will come closer to its fall launch.

Compression, not resolution, decides why some 1080p Blu-rays beat 4K streams

A report explains that streaming platforms must compress 4K video heavily to send it over the internet without buffering, which strips out fine details like film grain, shadow gradients, textures and complex motion data. A 1080p Blu-ray, by contrast, uses a much higher bitrate and preserves that visual information more faithfully, so it can look sharper in demanding scenes despite having fewer pixels.

Fields Medalist Heisuke Hironaka, who solved singularities problem, dies

Mathematician Heisuke Hironaka has died, according to an obituary published in Nature. He was renowned for proving the resolution of singularities in algebraic geometry, a landmark result that addressed how to mathematically smooth out irregular points such as peaks, edges and self-crossings within geometric shapes.

Alienware's AW3926QW brings 5K2K resolution to a new 39-inch ultrawide OLED format

Alienware has released the AW3926QW, a 39-inch ultrawide gaming monitor sitting between the common 34-inch and 45-inch OLED sizes. It uses a 5120 x 2160 panel, giving it the same vertical resolution as a standard 4K screen so it can display 4K content at full clarity, unlike typical 3440 x 1440 ultrawides. It also delivers OLED-level contrast, reaching a true zero-nit black for near-infinite contrast ratio.

Wyze launches $40 pan-tilt indoor camera with a retractable privacy lens

Wyze has released the Indoor Cam Pan, a $39.98 indoor security camera that rotates 360 degrees and tilts 103 degrees, with a lens that can fold completely into its body for privacy. It records at 2K resolution, includes AI motion tracking that filters out robot vacuums and non-target movement, night vision, a microSD slot supporting up to 512GB, and a built-in speaker and microphone for two-way audio and a 95-decibel alarm.