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Sloan Kettering

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AI model from Memorial Sloan Kettering identifies brown fat on PET-CT scans

Researchers at Memorial Sloan Kettering Cancer Center built an AI tool to automatically detect brown adipose tissue (BAT) in 18F-FDG-PET-CT scans, expanding an existing patient cohort with a new dataset spanning April 2018 to July 2024. The retrospective study linked BAT presence to clinical and demographic data, including BMI and outdoor temperature, to examine associations with cardiometabolic disease risk.

Study links sugar-heavy diets to worse gut microbiome damage during antibiotic treatment in transplant patients

Researchers at Memorial Sloan Kettering tracked meal-by-meal food intake for adult stem cell transplant patients from 2017 to 2022, recording what percentage of each dish patients actually ate. The team then analyzed how these dietary patterns interacted with antibiotic exposure and gut microbiome recovery, using neutrophil engraftment and survival data as clinical outcomes.

Revlimid successor daraxonrasib shrinks tumors in early lung cancer trial

A week after its US approval for advanced pancreatic cancer, the drug daraxonrasib has shown early promise against non-small cell lung cancer, the most common form of the disease. In a small trial published in the New England Journal of Medicine, tumors shrank in over 30% of patients whose cancers carried mutations in RAS family proteins and who had already failed other treatments. A larger randomized trial comparing daraxonrasib to standard chemotherapy is now underway.