GoKawiilResearchers identify rare cortical neurons that can trigger sleep in mice
Scientists at Albert Einstein College of Medicine identified a small population of cortical inhibitory neurons, called Sst-Chodl cells, that make up about one percent of the cortex's inhibitory neurons. Activating these cells in mice was enough to induce sleep, showing the cortex itself can generate slow-wave sleep rhythms rather than merely responding to signals from deeper brain regions. The team spent years developing a genetic labeling method precise enough to isolate this rare cell type from more abundant, similar neurons.