GoKawiilCDC survey: 27 million US adults used GLP-1 drugs in 2025, many off-label
A CDC study analyzing survey data from over 8,000 US adults found that 9.8% of Americans, or roughly 27 million people, used a GLP-1 medication in 2025. Nearly half of those users altered how they took the drug—skipping doses, delaying refills or taking smaller amounts than prescribed—and more than half of that group cited cost or availability as the reason. At least 23% of users took a compounded version of the drug, with another 9% unsure whether their medication was compounded.