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University of Kentucky study restores mice sleep by targeting immune cells, not plaques

Researchers at the University of Kentucky found that temporarily depleting microglia, the brain's resident immune cells, restored more than two hours of sleep per day in mice with Alzheimer's-like brain changes, without removing amyloid plaques. The team, led by Shannon L. Macauley and first author Nicholas J. Constantino, published the findings in Alzheimer's & Dementia, showing mice also spent more time in deep, restorative sleep stages.

NUS researchers build washable fiber display that turns fabric into a touchscreen

Engineers at the National University of Singapore, led by Fu Heng, created millimeter-thick fibers embedding thousands of LED chips and pressure sensors, woven into a sweater sleeve to act as an interactive display. The fibers survived 50 machine washes and 1,000 bending cycles, and can be produced up to 10 meters long with added components like microphones and temperature sensors, though the prototype still needs external batteries and controllers.

Northwestern Physicists Isolate Single Positron in Trap for One Month

A Northwestern University team led by Gerald Gabrielse trapped an individual positron, the antimatter counterpart of the electron, for a full month. They generated it from decaying sodium-22 atoms, slowed it using a cold tungsten crystal, then confined it in a near-absolute-zero vacuum using combined electric and magnetic fields with no physical walls. The result was published in Physical Review Letters.

New documentary revisits Elizabeth Holmes with intimate home footage

Filmmakers Nathan Fielder and Lance Oppenheim spent time documenting Elizabeth Holmes and her partner Billy Evans at home with their children, beginning around a month before she started serving her prison sentence in May 2023. The resulting film reportedly features extensive close-up footage of Holmes interacting with Fielder and her family, revisiting the Theranos founder's story after her 2022 fraud conviction.

Cambridge-developed $10 spectrometer chip aims for wearable health monitoring

Researchers at the University of Cambridge, working with spin-out GlitterinTech, have built a low-cost optical spectrometer only centimeters in size. Called a convolutional spectrometer, it uses the convolution theorem to analyze light, which the team says yields accuracy and measurement range exceeding existing compact spectrometer designs.

Penn researchers use AI to analyze Reddit reports on unapproved retatrutide use

University of Pennsylvania scientists analyzed roughly 150,000 Reddit posts from about 40,000 users to study self-reported effects of retatrutide, an experimental GLP-1 weight-loss drug not yet approved by regulators but obtained by some people in unapproved forms online. The study, published in JAMA Network Open, found that increased appetite was the most commonly reported symptom among classifiable complaints—contrary to the drug's hunger-suppressing design and the digestive issues emphasized in Phase 2 trials.

Unpublished Schrödinger manuscript found in Austrian library challenges his reputed views

Physics historian Flavio Del Santo of the University of Geneva has uncovered a previously unpublished three-page manuscript by Erwin Schrödinger that had sat unnoticed in an Austrian library for over 80 years. In it, Schrödinger argues that indeterminism—true randomness in nature—predates quantum mechanics itself, a position that runs counter to the common portrayal of him as uneasy with quantum randomness.

Ohio State researchers build system to digitally capture and transmit smells

Ohio State University researchers have developed a two-part system—an AI-powered 'e-nose' and a wearable receiver called a Scentronic—that can detect an odor and recreate it remotely. The Scentronic, available as a wristband, handheld device or necklace, uses a piezoelectric atomizer and Wi-Fi/cloud connection to reproduce scents; in tests, 16 participants correctly identified all five smells used (cake, beer, red wine, coffee and oranges).

Finance grad shifts career path after teaching himself workflow automation tool n8n

A recent Loyola University Chicago finance graduate, who spent four summers as a Financial Planning and Analysis intern at a healthcare company, describes teaching himself the workflow automation platform n8n during his final semesters of school. He frames this as a deliberate effort to feel uncomfortable and incompetent on purpose, after years of side hustles ranging from sneaker reselling to rug tufting, and says the experience reshaped his view of his career options beyond the finance track he thought was fixed.

Polymarket pulls betting market on Cornell gang-rape case after backlash

Polymarket hosted a market titled 'Any of the Cornell 7 charged with a felony sex crime?' for nearly three weeks starting September 30, tied to a civil suit alleging seven Cornell students drugged and gang-raped a former student. After Defector and Front Office Sports reported on the market and women's rights advocates criticized it online, Polymarket removed the listing, saying it was responding to public sentiment.

Cambridge epidemiologist builds citizen networks to diagnose unhealthy cities

Tolullah Oni, a public-health researcher at the University of Cambridge who calls herself an urban epidemiologist, treats cities as patients by tracking factors like air quality and heat that affect residents' health. In 2019 she founded the non-profit UrbanBetter, which trains local citizens and researchers to collect and analyze their own urban data. The group's civic arm, Cityzens Hubs, now operates in 11 African cities plus Bogotá and Bangkok, alongside a research centre in Cambridge.

Geneticist Robert Williamson, who mapped cystic fibrosis and muscular dystrophy genes, dies

Robert Williamson, a geneticist who used DNA markers to locate disease-linked genes on human chromosomes, has died. His research mapped the locations of the genes associated with cystic fibrosis and Duchenne muscular dystrophy, work that enabled carrier testing and expanded genetic counselling for affected families. He also studied globin genes and thalassaemia, helping develop prenatal diagnosis methods, and later advised governments in the UK and Australia on science policy and bioethics.