GoKawiilUniversity of Kentucky study restores mice sleep by targeting immune cells, not plaques
Researchers at the University of Kentucky found that temporarily depleting microglia, the brain's resident immune cells, restored more than two hours of sleep per day in mice with Alzheimer's-like brain changes, without removing amyloid plaques. The team, led by Shannon L. Macauley and first author Nicholas J. Constantino, published the findings in Alzheimer's & Dementia, showing mice also spent more time in deep, restorative sleep stages.