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The provided text consists entirely of a bibliography of scientific citations related to organ transplant shortages, pig-to-human xenotransplantation research, and immune rejection mechanisms. No article content, study results, or news event is included beyond these reference entries.
Stanford University researchers led by Sergiu Pașca transplanted lab-grown human brain organoids into mice bred to lack most of their cerebral cortex. The transplanted tissue survived and formed functional connections to the animals' brains and spinal cords, according to a study published in Nature. The team describes it as the most extensive integration of human brain cells into an animal achieved to date.
Scientists are developing gene-edited pig organs as a potential solution to the chronic shortage of human transplant organs. Researchers involved say the work could fundamentally change how transplantation is practiced if organ scarcity is eliminated.