Researchers used zebrafish larvae, including alox5a and hcar1-4 mutant lines, to study how a lipid signaling molecule called 5-oxoETE helps cells detect epithelial injury and recover from it. They examined wound healing in fin amputation assays and chemical colitis induced by DSS in the larval intestine, tracking leukocyte recruitment and apoptosis across genetic backgrounds. The work was conducted under institutional animal care oversight at Memorial Sloan Kettering Cancer Center.
nature.com
· 2026-10-07
Researchers studying zebrafish (referred to in the methods as D. cerebrum) examined how neurons detect social actions of other fish to coordinate group escape responses. The work combined behavioural tracking with brain imaging using a transgenic calcium-indicator line, observing fish from larval stages through adulthood in controlled lab conditions.
nature.com
· 2026-09-23
Researchers developed a light-sheet microscopy method capable of recording cellular-level activity simultaneously across all organs in larval zebrafish and the small, transparent adult fish species Danionella cerebrum. Using carefully controlled husbandry and automated analysis pipelines, the team was able to track physiological signals body-wide rather than in a single organ, revealing coordinated circuits linking the brain to peripheral tissues.
nature.com
· 2026-09-09
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