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32071.
Non-equilibrium snapshots of ligand efficacy at the μ-opioid receptor (feeds.nature.com)
32072.
NAC controls nascent chain fate through tunnel sensing and chaperone action (feeds.nature.com)
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Daily briefing: Explore 2025 with Leif Penguinson (feeds.nature.com)
32074.
I wish people were more public (news.ycombinator.com)
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Honey: all the news about PayPal’s alleged scam coupon app (theverge.com)
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Are 'Geek Gifts' Becoming Their Own Demographic? (slashdot.org)
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LVM Thin Provisioning (2016) (news.ycombinator.com)
32078.
Fabrication Techniques Using Myco-Materials (news.ycombinator.com)
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Handheld PC Community Forums (news.ycombinator.com)
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Disney Imagineering Debuts Next-Generation Robotic Character, Olaf (news.ycombinator.com)
32081.
'Confused' Waymos Stopped in Intersections During San Francisco Power Outage (slashdot.org)
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‘The Vampire Lestat’ Showrunner Teases Louis & Claudia’s Returns (gizmodo.com)
32083.
MacBook Pro ‘overhaul’ launching as soon as next year: Here are five upgrades to expect (9to5mac.com)
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The gift card accountability sink (news.ycombinator.com)
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Today's NYT Connections Hints, Answers and Help for Dec. 22, #925 (cnet.com)
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Show HN: Rust/WASM lighting data toolkit – parses legacy formats, generates SVGs (news.ycombinator.com)
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A guide to local coding models (news.ycombinator.com)
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More on whether useful quantum computing is “imminent” (news.ycombinator.com)
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Rue: Higher level than Rust, lower level than Go (news.ycombinator.com)
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You can now tweak how warm and enthusiastic ChatGPT's responses are (engadget.com)
32091.
Do Gamers Hate AI? Indie Game Awards Disqualifies 'Clair Obscur' Over GenAI Usage (slashdot.org)
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Waymo pauses robotaxi service in San Francisco after blackout chaos — Musk says Tesla car service unaffected (cnbc.com)
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Opinion | The U.S. Can’t Get Xi Hooked on Nvidia Chips (feeds.content.dowjones.io)
32094.
Redis vs. BoltCache (news.ycombinator.com)
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Package Forge: The Lesser Known Snap/Flatpak Alternative Without Distro Lock-In (slashdot.org)
32096.
GuliKit's $20 mod makes the ROG Xbox Ally's joysticks drift-free (engadget.com)
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Agent autonomy without guardrails is an SRE nightmare (venturebeat.com)
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I can't upgrade to Windows 11, now leave me alone (news.ycombinator.com)
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The Going Dark initiative or ProtectEU is a Chat Control 3.0 attempt (news.ycombinator.com)
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Mullvad VPN: "This is a Chat Control 3.0 attempt." (news.ycombinator.com)
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