GoKawiil
Tech News
A new review synthesizes the evolving treatment landscape for metabolic dysfunction-associated steatohepatitis (MASH), the liver disease formerly called NASH, drawing on updated epidemiological data, revised diagnostic terminology, and studies on liver fibrosis assessment. It outlines existing approaches alongside emerging therapies aimed at addressing the disease's metabolic, cardiovascular and cancer-related complications.
A scientist who has logged 10,000 papers in a reference manager over 13 years describes moving from trying to read every paper closely to a selective, task-driven approach to the literature. The piece also warns that AI tools like ChatGPT, despite improved search and summarization, still risk producing uncritical or fabricated citations if used without careful reading.
Conservation Through Public Health, working with the EU-Africa NESTLER project, gathered disease samples from cattle and poultry near Bwindi Impenetrable National Park and combined them with gorilla health monitoring records. The pooled data is being fed into AI models designed to predict zoonotic disease outbreaks before they spread among wildlife, livestock and people, shifting the group's approach from reactive response to proactive prevention.
A study of more than 70,000 people published in Nature Medicine found that those who received the current Shingrix shingles vaccine, rather than an older formulation, had a reduced risk of heart disease and heart failure. Researchers compared recipients of the two vaccine types rather than vaccinated versus unvaccinated people, a design meant to avoid the bias seen in earlier studies where healthier people were more likely to get vaccinated.
Researchers at KAIST and the Institute for Basic Science, using APP/PS1 and 5×FAD mouse models along with human brain tissue from a Seoul National University Hospital bank, examined the role of the ERBB4 protein in excitatory neurons. Their experiments indicate that abnormal expression of ERBB4 in these neurons contributes to the progression of Alzheimer's disease-related brain changes.
Researchers examined brain tissue from 338 former NFL players who died recently and found that the vast majority showed signs of chronic traumatic encephalopathy, a degenerative brain disease linked to repeated head trauma. The new findings suggest the condition is more widespread among professional football players than previously estimated.
Doctors documented a 15-year-old whose prolonged, heavy cannabis use led to episodes of severe cyclic vomiting and screaming, known as scromiting. The condition triggered a dangerous vitamin B1 deficiency that caused a neurological disease typically seen in chronic alcoholics, in which brain function began to deteriorate.
A commentary describes how artificial intelligence systems can analyze existing movement and balance data to catch subtle physical changes before they become clinically obvious symptoms. This approach reframes AI as a preventive tool rather than just a diagnostic aid used after disease onset.
The FDA has cleared PrecivityAD2, a blood test built on technology from Washington University School of Medicine, to help identify amyloid plaques linked to Alzheimer's disease. Developed by WashU spinoff C2N Diagnostics, the test uses high-resolution mass spectrometry to quantify biomarkers with over 90% accuracy, offering a less invasive option than spinal taps or brain imaging.