Published on: 2025-06-01 22:13:35
“Those chemical modifications that decorate [histones] and modify gene expression — they’re metabolites, full stop,” said Finley, the cancer biologist. “Chemical modifications themselves are metabolites, and their removal is dependent on metabolites.” Fifteen years ago, when Kathryn Wellen was a postdoc studying cancer cells, she discovered that the epigenetic marks on histones change in response to the presence of nutrients. When food is plentiful, mitochondria make a metabolite called acetyl-
Keywords: activity cells genes metabolic nucleus
Find related items on AmazonPublished on: 2025-07-14 02:03:37
A recurring theme of this Substack are my attempts to build out an accessible curriculum for hobby electronics. The target audience are folks who are no longer content with dumbed-down analogies, but who aren’t keen on academic textbooks brimming with obtuse jargon and advanced calculus. I’m particularly fond of the following foundational articles: Today, I’d like to take a step back and tackle a more basic question that isn’t always satisfactorily answered in high school: what is electricity a
Keywords: atom don electron electrons nucleus
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