GoKawiilAdelaide researchers use tumor-targeted nanoparticles to reprogram cancer-fighting immune cells
University of Adelaide scientists led by Chunxia Zhao designed 'smart' nanoparticles that ferry mRNA specifically to tumor-associated macrophages, prompting them to produce CXCL9, a molecule that summons T cells to attack cancer. The approach, described this week in Science Advances, aims to reverse how tumors normally hijack macrophages to block immune attacks.