TenK10K study links 1,042 blood samples to chromatin accessibility atlas
Researchers built a single-cell chromatin accessibility atlas using blood samples from 1,042 individuals drawn from the TenK10K phase I cohort, combining the Tasmanian Ophthalmic Biobank, BioHeart and Liquid Biopsy Biobank cohorts. The team used 10X Genomics single-cell ATAC-seq technology on 952 of these donors to map genetic variants influencing chromatin accessibility, a step toward understanding disease risk at the cellular level.