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Preparedness

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AlphaFold database adds 8,000+ viral protein complex structures

EMBL-EBI's AlphaFold Protein Structure Database has been expanded with more than 8,000 predicted structures of interacting protein pairs from viruses spanning 23 families that infect humans, including monkeypox virus. The addition, part of a new 'pandemic preparedness portal', builds on an earlier 2024 update that added 1.7 million interacting protein pairs from 20 organisms such as humans and tuberculosis bacteria.

OpenAI classifies GPT-6 Astra at 'Critical' cybersecurity risk level

OpenAI disclosed that its newly deployed GPT-6 Astra model is the first widely released system to hit the 'Critical' threshold in the company's Preparedness Framework for cybersecurity, meaning it can autonomously find and exploit zero-day vulnerabilities in hardened systems. In testing, Astra reportedly uncovered two previously unknown real-world vulnerabilities, which OpenAI says it is now disclosing to the affected software maintainers. The company added new safeguards including stronger jailbreak resistance and monitoring, and says Astra shows fewer safety violations than its predecessor, GPT-5.6 Sol.

Seismologists Warn West Coast Remains Underprepared for Major Earthquake

Experts assessing U.S. West Coast earthquake readiness say that despite decades of warnings about a potential massive quake, significant gaps remain in infrastructure, building codes, and emergency response systems. Their evaluation points to aging structures, inconsistent retrofitting, and insufficient public preparedness as key vulnerabilities that would be exposed when a major seismic event eventually strikes.

OpenAI classifies upcoming Astra model as 'Critical' risk under cybersecurity framework

OpenAI announced that its forthcoming Astra AI model is the first to cross the company's 'Critical' cybersecurity capability threshold, meaning it can discover unknown vulnerabilities and exploit them autonomously without human step-by-step direction. The company says Astra will still launch soon, but access to its most sensitive cybersecurity abilities will be restricted, with further safety details to come in a system card at release.

AI lab designates 'Astra' model as first to cross critical cybersecurity risk threshold

The company behind the Astra model says new testing shows it has crossed a 'Critical' cybersecurity capability threshold under its Preparedness Framework, meaning it could independently discover unknown vulnerabilities and craft exploits against well-defended systems without step-by-step human guidance. This is the first model the company has classified at that severity level, prompting delays to strengthen safeguards before release.