GoKawiilScientists identify chimeric mRNAs that produce functional proteins in immune cells
Researchers used long-read direct RNA sequencing on Oxford Nanopore's PromethION platform to identify chimeric messenger RNAs—transcripts formed by joining sequences from two different genes—in mammalian immune cells. The study found that some of these hybrid transcripts are not just sequencing artifacts but actually get translated into functional proteins that play roles in immunity.