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Skeletons

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Ancient teeth reveal earliest known habitual drug use in Indonesia

Researchers analyzing two skeletons unearthed in Indonesia found heavy tooth wear and traces of arecoline, a psychoactive compound found in betel nuts. One skeleton dates back 16,000 to 25,000 years, suggesting the individuals regularly chewed or sucked on betel nuts long before the practice became widespread. The findings, published in Science Advances, push back the timeline for humanity's earliest documented drug habits.