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Amateur Biochemist Claims Garage Synthesis of ChatGPT-Designed Schizophrenia Drug

Douglas Yao, a self-taught chemist working outside any pharmaceutical company, says he used ChatGPT to design a new compound called PAC-3310, targeting the same receptor as the approved antipsychotic Cobenfy. He claims to have built a chemistry lab in his garage, synthesized the compound himself, and is now testing it in cell lines and mice, part of a broader effort to generate thousands of AI-designed drug candidates.

Neo Geo AES+ console delayed nearly two years to September 2027

Plaion Replai has pushed back the launch of its Neo Geo Advanced Entertainment System+ remake from November 2025 to September 16, 2027. The company cites overwhelming demand plus a global memory chip shortage fueled by AI infrastructure investment as reasons for the delay. Pricing remains unchanged, with the standard edition at $250 and the 35th anniversary bundle at $350.

DOJ issues second request for data in Fox-Roku $22B merger review

The Justice Department has formally asked Fox and Roku to submit additional documents and data as part of a deeper antitrust review of Fox's proposed $22 billion acquisition of Roku. The move, known as a second request, is a standard but significant step signaling regulators have unresolved questions after reviewing the companies' initial filings.

Prime Video unveils full trailer for Mike Flanagan's Carrie reimagining

Prime Video has released the official trailer for Mike Flanagan's six-episode Carrie miniseries, based on Stephen King's novel. Flanagan says the series isn't a straight remake of the 1976 story or Brian De Palma's film, but instead expands the world of Carrie White and her tormentors for a modern audience. The cast includes Summer H. Howell as Carrie, Siena Agudong as Sue Snell, and Amber Midthunder as Miss Desjardin.

Modder Lets GTA V Players Destroy Fake Flock License Plate Cameras for Cash

Artist Morry Kolman released a Grand Theft Auto V mod called Grand Theft Automated License Plate Reader, which scatters 235 replica Flock Safety cameras across Los Santos and rewards players $600 for each one they destroy. The mod also mimics real-world surveillance behavior, extending police chase cooldowns near cameras and occasionally triggering false police responses to mirror reported ALPR errors.

Psychiatrist coins 'prolific AI psychosis' to describe hollow high-volume AI output

A psychiatrist continues a series defining AI-related psychological patterns, this time focusing on what he calls 'prolific AI psychosis.' He describes it as a state where a person churns out massive volumes of AI-generated work—like thousands of lines of code or text—without a corresponding increase in real value, sometimes even destroying value in the process.

GNU Radio now runs fully in-browser via WebAssembly port

A new project compiles the GNU Radio DSP engine and its Qt GUI sinks to WebAssembly, letting users build and run software-defined radio flowgraphs directly in a browser tab without installing Python or GNU Radio. It supports the same .grc flowgraph files as the desktop app, includes sample flowgraphs and IQ recordings, and can connect to RTL-SDR, PlutoSDR or HackRF hardware through WebUSB.

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