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Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s

wired.com Emily Mullin 2026-03-02 14:01:00

Eli Lilly’s daily anti-obesity pill orforglipron appears to be as good at spurring weight loss and lowering blood sugar in diabetes patients as popular injectable GLP-1 drugs like Ozempic, according to new data from a Phase 3 trial. The results were announced today at the annual meeting of the American Diabetes Association and published in the New England Journal of Medicine. Eli Lilly is the maker of the blockbuster GLP-1 drug tirzepatide, approved as Mounjaro for type 2 diabetes and Zepbound

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Surgery Still Beats Ozempic and Other GLP-1 Drugs in Real-World Weight Loss Study

gizmodo.com Ed Cara 2026-03-11 18:05:43

When it comes to weight loss, surgery still reigns supreme. Research out today shows that people undergoing bariatric surgery tend to lose significantly more weight than people taking the newest, most effective GLP-1 medications for obesity. Scientists at New York University conducted the study, which analyzed real-world data from obesity patients. People who received surgery lost five times more weight over a two year span on average than those who were prescribed a GLP-1 drug, they found. The

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A New Obesity Pill May Burn Fat Without Suppressing Appetite

wired.com Emily Mullin 2026-03-15 05:00:00

An experimental obesity pill that works in a different way from the wildly popular Ozempic may help people lose weight, according to results from a small, preliminary human trial. Ozempic and other GLP-1 drugs reduce food intake by stimulating a feeling of fullness. They act on the brain to promote satiety and on the gut to slow the movement of food through the stomach, helping people feel full longer. As a result, people on the drugs lose weight because they eat less. But a new drug may be ab

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Broken legs and ankles heal better if you walk on them within weeks

news.ycombinator.com Lydia Denworth 2025-11-12 22:36:06

Twenty years ago my husband, Mark, broke his left ankle and was in a cast and on crutches for nearly two months. Last year he broke the other ankle. But this time, after surgery, his doctor surprised us by instructing Mark to walk on it two weeks later. It turns out the standard advice to stay off a broken leg bone for at least six weeks is based less on scientific evidence and more on cultural caution—physicians like to play it safe. But now studies show that complications are no more likely w

Topics: bearing bone early weeks weight
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