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Kyoto University team develops pain reliever comparable to morphine

news.ycombinator.com No Author 2026-01-11 02:47:18

A Kyoto University research team has developed a pain-reliever that is comparable to morphine but does not have serious side effects. Morphine, often administered to cancer patients, has serious adverse effects such as breathing issues and addiction. According to the team, the newly developed drug, Adriana, is a groundbreaking painkiller, which works on a completely different mechanism to morphine and other existing synthetic opioids. The drug has the potential to revolutionize pain control in

Topics: drug morphine pain patients team

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Using drone imagery and AI to rapidly assess damage after hurricanes and floods

news.ycombinator.com Lesley Henton 2026-01-07 03:22:18

A tool developed at Texas A&M University is set to transform how emergency responders assess damage after disasters. The technology, known as CLARKE (Computer vision and Learning for Analysis of Roads and Key Edifices) uses artificial intelligence and drone imagery to evaluate damage to buildings, roads and other infrastructure in a matter of minutes. CLARKE was created by a team of researchers led by Tom Manzini, a Ph.D. candidate in computer science and engineering, and Dr. Robin Murphy, a pi

Topics: clarke damage drone florida murphy

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PHP 8.5 adds pipe operator

news.ycombinator.com Unknown 2026-01-11 03:13:43

PHP 8.5, due out November of this year, will bring with it another long-sought-after feature: the pipe operator ( |> ). It's a small feature with huge potential, yet it still took years to happen. What is a pipe operator? The pipe operator, spelled |> , is deceptively simple. It takes the value on its left side and passes it as the single argument to a function (or in PHP's case, callable ) on its right side: $result = "Hello World" |> strlen(...) // Is equivalent to $result = strlen("Hello W

Topics: function operator php pipe pipes

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Today's NYT Mini Crossword Answers for Tuesday, Aug. 5

cnet.com See Full Bio 2026-01-11 00:54:00

Gael Cooper CNET editor Gael Fashingbauer Cooper, a journalist and pop-culture junkie, is co-author of "Whatever Happened to Pudding Pops? The Lost Toys, Tastes and Trends of the '70s and '80s," as well as "The Totally Sweet '90s." She's been a journalist since 1989, working at Mpls.St.Paul Magazine, Twin Cities Sidewalk, the Minneapolis Star Tribune, and NBC News Digital. She's Gen X in birthdate, word and deed. If Marathon candy bars ever come back, she'll be first in line.

Topics: 1989 author cooper gael journalist

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HelloFresh Coupon Codes: 55% Off + Free Meals - August 2025

wired.com Matthew Korfhage 2026-01-11 04:15:00

Leveraging meal kit coupons is the extreme couponing of our times—a capitalism hack-a-thon right up there with trial yoga classes and attempting to cancel your Adobe subscription. Meal kits like HelloFresh have always been a better deal than they get credit for, even at full price: It’s actually hard to recreate meal kit meals for less than you can get the recipes delivered to your home. But it’s especially worth it when you can find a HelloFresh coupon, promo code, or discount at more than half

Topics: discount discounts free hellofresh meal

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OpenAI Admits ChatGPT Missed Signs of Delusions in Users Struggling With Mental Health

futurism.com Unknown 2026-01-11 04:12:59

After over a month of providing the same copy-pasted response amid mounting reports of "AI psychosis", OpenAI has finally admitted that ChatGPT has been failing to recognize clear signs of its users struggling with their mental health, including suffering delusions. "We don't always get it right," the AI maker wrote in a new blog post, under a section titled "On healthy use." "There have been instances where our 4o model fell short in recognizing signs of delusion or emotional dependency," it

Topics: chatbot chatgpt mental openai users

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Deal: Only have one HDMI input? Multiply it with the Anker HDMI Switch

androidauthority.com Unknown 2026-01-11 05:05:12

Some monitors and TVs only have a single HDMI port. This is fine if your entertainment system is simple, but if you have multiple devices, it can get really annoying to plug and unplug the HDMI port constantly. This is when something like the Anker HDMI Switch comes in handy. It can turn one HDMI input into two, and you can take it home for a mere $9.99 right now! Buy the Anker HDMI Switch for just $9.99 ($10 off) This offer is available from Amazon. It’s a “limited time deal,” meaning it shoul

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All 2025 Motorola Razr foldables are on sale!

androidauthority.com Unknown 2026-01-11 08:16:01

Ryan Haines / Android Authority The Motorola Razr and Razr Plus deals come from Amazon. On the other hand, the Motorola Razr Ultra offer is available directly from Motorola’s website. Motorola Razr 2025 Motorola Razr 2025 Motorola Razr 2025 The most affordable 2025 Razr A good looking 6.9-inch folding display is paired with a 3.6-inch external display to make up a compact folded phone, with few compromises at full-size. The Motorola Razr 2025 is powered by a MediaTek Dimensity 7300X and 8GB o

Topics: 2025 display motorola phone razr

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People are using ChatGPT to write their text messages - here's how you can tell

zdnet.com Webb Wright 2026-01-11 06:00:14

Kirill Stytsenko/Getty Images ZDNET's key takeaways People are using AI to write sensitive messages to loved ones. Detecting AI-generated text is becoming more difficult as chatbots evolve. Some tech leaders have promoted this use of AI in their marketing strategies. Everyone loves receiving a handwritten letter, but those take time, patience, effort, and sometimes multiple drafts to compose. Most of us at one time or another have given a Hallmark card to a loved one or friend. Not because

Topics: ai chatgpt generated text using

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Tell HN: Anthropic expires paid credits after a year

news.ycombinator.com Unknown 2026-01-11 05:43:40

> Your organization “xxx” has $xxx Anthropic API credits that will expire on September 03, 2025 UTC. > > To ensure uninterrupted service, we recommend enabling auto-reload for your organization. When enabled, we’ll automatically add credits when your balance reaches a specified minimum. You can enable auto-reload in the Anthropic Console.

Topics: anthropic auto credits organization reload

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Deterministic Simulation Testing in Rust: A Theater of State Machines

news.ycombinator.com Unknown 2026-01-07 04:36:58

It's been just a year since we wrote about how we implemented deterministic simulation testing (DST) of our Go database (FrostDB). Since then, we have been hard at work writing our new database backed by object storage in Rust (read more here about why). In this blog post, I want to lay out the approach we took to build our new Rust database with DST principles front-and-center and how it compares to the approach we took with FrostDB. As a quick recap, DST tests are randomized full system integ

Topics: dst failure machines message state

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The history of the Schwartzian Transform (2016)

news.ycombinator.com Unknown 2026-01-07 03:15:38

The History of the Schwartzian Transform The history of the Schwartzian Transform is fascinating, full of intrigue, competing philosophies, and cross-language reluctant cooperation. The Schwartzian Transform is the name applied to a particular implementation of a cached-key sorting algorithm. The first public appearance is probably Randal Schwartz’s Usenet post on December 16, 1994 in response to Ken Brown’s request for help: I’m having trouble sorting on the *last* word of the last field in

Topics: people perl randal schwartzian transform

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Oxmiq Labs Inc.: Re-Architecting the GPU Stack: From Atoms to Agents

news.ycombinator.com Unknown 2026-01-11 08:46:58

Campbell – CA. Oxmiq Labs Inc., the all-new GPU software and IP startup founded by one of the world’s top GPU architects and visionaries, Raja Koduri, emerges from stealth after two years of intensive IP development. Raja has assembled a world-class team of GPU and AI architects with over 500 years of combined experience, hundreds of patents, and a collective track record of generating more than $100B in revenue at prior companies. The Opportunity: Modern computing has fundamentally shifte

Topics: ai gpu mihira oxmiq software

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Switch 2 Overheating? Nintendo Just Posted a Warning You Shouldn't Ignore

cnet.com See Full Bio 2026-01-11 04:01:27

Nintendo released its Switch 2 almost two months ago, and it sold close to 6 million units, according to the company's latest quarterly report. The new console has had a few hardware issues pop up, but Nintendo did confirm that it does have a bit of a heating problem. In a July 31 post on its X support account, Nintendo advised users to avoid playing the original Switch and the Switch 2 in high temperatures. The company says operating the consoles in a hot environment will raise the temperature

Topics: console mode nintendo switch temperature

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Jeh Aerospace nets $11M to scale the commercial aircraft supply chain in India

techcrunch.com Jagmeet Singh 2026-01-11 04:30:00

Indian startup Jeh Aerospace founders Vishal Sanghavi and Venkatesh Mudragalla have had a front row seat to the commercial aircraft sector and its growing production bottleneck. The two former Tata Group executives spent close to two decades in different positions at the company and worked on projects that included participation from global aerospace companies, including Boeing, Sikorsky, and Lockheed Martin. Now, armed with $11 million in Series A funding, the pair are working to ease global

Topics: aerospace jeh manufacturing sanghavi startup

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The Download: fixing ‘evil’ AI, and the White House’s war on science

technologyreview.com Charlotte Jee 2026-01-10 20:05:00

+ We’re starting to give AI agents real autonomy. But are they really ready for it? + What even is AI? Everyone thinks they know, but no one can agree. Here’s why that’s a problem. The must-reads I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology. 1 The US is losing its scientific supremacy Money and talent are starting to leave as a hostile White House ramps up its attacks. (The Atlantic $) + The foundations of America’s prosperity a

Topics: ai mit review tech technology

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Thingino: Open-Source Firmware for IP Cameras

news.ycombinator.com Unknown 2026-01-11 08:22:00

Supported Hardware Please note that we list not only the camera model, but also its SoC, image sensor, Wi-Fi module, and flash chip size. These must match to be supported by the firmware. We have found that some manufacturers change the hardware in different batches of the same module without notice. Indoor IP Cameras Bulb IP Cameras Outdoor IP Cameras IPC Modules Web Cameras Development Boards Teacup T31X Conditionally Supported Hardware Some brands protect their cameras by writing a

Topics: cameras hardware key soc supported

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‘Together’ Director Explains How that Wild Final Shot Was Made (Without AI)

gizmodo.com Germain Lussier 2026-01-11 09:30:38

Ever since its debut at Sundance earlier this year, fans of horror have had Michael Shanks’ new film, Together, on their radars. Neon picked it up out of the festival and, after some really creepy trailers and marketing, opened it in theaters last weekend with solid results. It’s a provocative, surprising, and incredibly disgusting movie with an ending viewers will not soon forget. An ending that was achieved through traditional methods of visual effects and without a hint of AI. As per that sp

Topics: ai alison film just shanks

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Sengled’s downfall shows the peril of relying on cloud connections for smart home control

theverge.com Jennifer Pattison Tuohy 2026-01-11 06:20:50

is a senior reviewer focused on smart home and connected tech, with over twenty years of experience. She has written previously for Wirecutter, Wired, Dwell, BBC, and US News. Posts from this author will be added to your daily email digest and your homepage feed. After repeatedly leaving customers without smart control of their lights, Sengled has been booted from Amazon’s Works With Alexa program. As first reported by TechHive, beginning August 1st, Sengled’s Alexa skill for controlling its l

Topics: alexa home matter sengled smart

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Amazon lays off more than 100 employees in Wondery unit as part of audio business restructuring

cnbc.com Annie Palmer 2026-01-11 14:02:18

The logo for Wondery is displayed on a smartphone in an arranged photograph taken in the Brooklyn borough of New York on Sept. 29, 2020. Amazon is laying off roughly 110 employees in its Wondery podcast division and the head of the group is leaving as part of a broader reshuffling of the company's audio unit. In a Monday note to staffers, Steve Boom, Amazon's vice president of audio, Twitch and games, said the company is consolidating some Wondery units under its Audible audiobook and podcasti

Topics: amazon audio boom shows wondery

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Hiroshima (1946)

news.ycombinator.com John Hersey 2026-01-08 14:59:38

I—A Noiseless Flash At exactly fifteen minutes past eight in the morning, on August 6, 1945, Japanese time, at the moment when the atomic bomb flashed above Hiroshima, Miss Toshiko Sasaki, a clerk in the personnel department of the East Asia Tin Works, had just sat down at her place in the plant office and was turning her head to speak to the girl at the next desk. At that same moment, Dr. Masakazu Fujii was settling down cross-legged to read the Osaka Asahi on the porch of his private hospital

Topics: father kleinsorge mr said tanimoto

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A YouTuber Is Folding and Unfolding the Samsung Galaxy Z Fold 7 200,000 Times

cnet.com See Full Bio 2026-01-11 12:06:00

Folding phones are no longer a fad. But they have moving parts that regular smartphones lack, and the constant folding and unfolding could eventually lead to failure. For the last few days, the host of Korean YouTube channel Tech-it has been folding and unfolding the Samsung Galaxy Z Fold 7 over and over and over, with the goal of doing 200,000 folds. The fold-a-thon is presumably meant to see how the redesigned hinge and flexible display hold up on Samsung's thinnest foldable yet. Tech-it's h

Topics: 000 fold folding phones samsung

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Today's Wordle Hints, Answer and Help for Aug. 5, #1508

cnet.com See Full Bio 2026-01-11 12:14:00

Looking for the most recent Wordle answer? Click here for today's Wordle hints, as well as our daily answers and hints for The New York Times Mini Crossword, Connections, Connections: Sports Edition and Strands puzzles. Today's Wordle puzzle is a fun word, and the letters aren't too rare. Want to know which letters show up the most in English words? We have a full list. If you need hints and the answer to today's Wordle puzzle, read on. Today's Wordle hints Before we show you today's Wordle a

Topics: answer hint hints today wordle

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ChatGPT Will Start Asking If You Need a Break. That May Not Be Enough to Snap a Bad Habit

cnet.com See Full Bio 2026-01-11 12:25:32

We've all been mid-TV binge when the streaming service interrupts our umpteenth-consecutive episode of Star Trek: The Next Generation to ask if we're still watching. That may be in part designed to keep you from missing the first appearance of the Borg because you fell asleep, but it also helps you ponder if you instead want to get up and do literally anything else. The same thing may be coming to your conversation with a chatbot. OpenAI said Monday it would start putting "break reminders" into

Topics: ai chatgpt like openai said

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What was the first computer to win a chess match against a world champion?

techspot.com Unknown 2026-01-11 18:40:00

Choose wisely! The correct answer, the explanation, and an intriguing story await. Correct Answer: IBM Deep Blue (1996) When Verizon bought AOL in 2015, how many people were still paying for dial-up Internet? IBM's Deep Blue became the first computer to defeat a reigning world chess champion under standard tournament time controls, a major milestone in both chess and artificial intelligence history. On February 10, 1996, Deep Blue won the first game of a six-game match against Garry Kasparov

Topics: blue chess deep kasparov world

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Hims & Hers stock falls 10% on revenue miss

cnbc.com Ashley Capoot 2026-01-11 18:54:05

The Hers app arranged on a smartphone in New York on Feb. 12, 2025. Shares of Hims & Hers Health fell 9% in extended trading on Monday after the telehealth company reported second-quarter results that missed Wall Street's expectations for revenue. Here's how the company did based on average analysts' estimates compiled by LSEG: Earnings per share: 17 cents adjusted vs. 15 cents expected 17 cents adjusted vs. 15 cents expected Revenue: $544.8 million vs. $552 million expected Revenue at Hims

Topics: cents expected hims million quarter

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ChatGPT rockets to 700M weekly users ahead of GPT-5 launch with reasoning superpowers

venturebeat.com Michael Nuñez 2026-01-11 17:42:05

Want smarter insights in your inbox? Sign up for our weekly newsletters to get only what matters to enterprise AI, data, and security leaders. Subscribe Now OpenAI’s ChatGPT will reach 700 million weekly active users this week, the company announced Monday, cementing its position as one of the fastest-adopted software products in history just as the company prepares to release its most powerful language model yet. The surge is a 40 percent jump from the 500 million weekly users ChatGPT had at

Topics: ai billion chatgpt openai users

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iPhone 17 Pro, Max and Air: Release dates, colors and everything else you need to know about Apple's new phones

engadget.com Unknown 2026-01-11 18:23:56

After seeing the changes coming with iOS 26, we're ready to finally see Apple's newest collection of smartphones: the iPhone 17 lineup. While that's still more than a month away — assuming Apple sticks to its usual release schedule — we haven't been left completely in the dark about what the new phones will look like. As with most unreleased iPhone models, rumors and leaks have trickled in about the hardware side ahead of the official introduction. Here's what we're expecting and what we can rea

Topics: 17 air apple iphone new

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Show HN: I made a competitive debating game(like chess.com but for debating)

news.ycombinator.com Unknown 2026-01-11 18:07:50

Challenge your ideas, climb the leaderboard, and join a vibrant community of thinkers. Sharpen Your Mind Engage in thoughtful debates that challenge your perspectives and improve your critical thinking skills. Climb the Rankings Earn ELO points for winning debates and see how you stack up against other debaters on our leaderboard.

Topics: challenge climb critical debates leaderboard

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Today's NYT Strands Hints, Answers and Help for Aug. 5 #520

cnet.com See Full Bio 2026-01-11 17:00:03

Looking for the most recent Strands answer? Click here for our daily Strands hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle, Connections and Connections: Sports Edition puzzles. Today's NYT Strands puzzle is a tough one -- and at lease one answer is especially tricky to unscramble. If you need hints and answers, read on. I go into depth about the rules for Strands in this story. If you're looking for today's Wordle, Connections and Mini Crossword a

Topics: hints puzzle strands today words

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Latest Tech News

Kyoto University team develops pain reliever comparable to morphine

Using drone imagery and AI to rapidly assess damage after hurricanes and floods

PHP 8.5 adds pipe operator

Today's NYT Mini Crossword Answers for Tuesday, Aug. 5

HelloFresh Coupon Codes: 55% Off + Free Meals - August 2025

OpenAI Admits ChatGPT Missed Signs of Delusions in Users Struggling With Mental Health

Deal: Only have one HDMI input? Multiply it with the Anker HDMI Switch

All 2025 Motorola Razr foldables are on sale!

People are using ChatGPT to write their text messages - here's how you can tell

Tell HN: Anthropic expires paid credits after a year

Deterministic Simulation Testing in Rust: A Theater of State Machines

The history of the Schwartzian Transform (2016)

Oxmiq Labs Inc.: Re-Architecting the GPU Stack: From Atoms to Agents

Switch 2 Overheating? Nintendo Just Posted a Warning You Shouldn't Ignore

Jeh Aerospace nets $11M to scale the commercial aircraft supply chain in India

The Download: fixing ‘evil’ AI, and the White House’s war on science

Thingino: Open-Source Firmware for IP Cameras

‘Together’ Director Explains How that Wild Final Shot Was Made (Without AI)

Sengled’s downfall shows the peril of relying on cloud connections for smart home control

Amazon lays off more than 100 employees in Wondery unit as part of audio business restructuring

Hiroshima (1946)

A YouTuber Is Folding and Unfolding the Samsung Galaxy Z Fold 7 200,000 Times

Today's Wordle Hints, Answer and Help for Aug. 5, #1508

ChatGPT Will Start Asking If You Need a Break. That May Not Be Enough to Snap a Bad Habit

What was the first computer to win a chess match against a world champion?

Hims & Hers stock falls 10% on revenue miss

ChatGPT rockets to 700M weekly users ahead of GPT-5 launch with reasoning superpowers

iPhone 17 Pro, Max and Air: Release dates, colors and everything else you need to know about Apple's new phones

Show HN: I made a competitive debating game(like chess.com but for debating)

Today's NYT Strands Hints, Answers and Help for Aug. 5 #520

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