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Scientists Launch Wild New Project to Build a Human Genome From Scratch

gizmodo.com Natalia Mesa 2025-08-23 14:00:04

A team of UK-based researchers is going where no scientist has dared to go—writing artificial human DNA from scratch. They’re hoping the project will answer fundamental questions about the human genome and transform our understanding of health and disease. But the research topic is, for obvious reasons, controversial. Scientists have largely steered clear of trying to create full synthetic human genomes, wary of propelling us into a dystopian, Gattaca-esque future full of designer babies. Now,

Topics: create genome genomes human researchers

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Hollywood’s pivot to AI video has a prompting problem

theverge.com Charles Pulliam-Moore 2025-08-23 15:00:00

is a reporter focusing on film, TV, and pop culture. Before The Verge, he wrote about comic books, labor, race, and more at io9 and Gizmodo for almost five years. It has become almost impossible to browse the internet without having an AI-generated video thrust upon you. Open basically any social media platform, and it won’t be long until an uncanny-looking clip of a fake natural disaster or animals doing impossible things slides across your screen. Most of the videos look absolutely terrible.

Topics: ai asteria generative mooser people

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From hallucinations to hardware: Lessons from a real-world computer vision project gone sideways

venturebeat.com Shruti Tiwari 2025-08-23 10:05:00

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more Computer vision projects rarely go exactly as planned, and this one was no exception. The idea was simple: Build a model that could look at a photo of a laptop and identify any physical damage — things like cracked screens, missing keys or broken hinges. It seemed like a straightforward use case for image models and large language models (

Topics: agents damage image images model

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The AI Backlash Keeps Growing Stronger

wired.com Reece Rogers 2025-08-23 01:30:00

Before Duolingo wiped its videos from TikTok and Instagram in mid-May, social media engagement was one of the language-learning app’s most recognizable qualities. Its green owl mascot had gone viral multiple times and was well known to younger users—a success story other marketers envied. But, when news got out that Duolingo was making the switch to become an “AI-first” company, planning to replace contractors who work on tasks generative AI could automate, public perception of the brand soured

Topics: ai duolingo generative people tasks

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AI agents are hitting a liability wall. Mixus has a plan to overcome it using human overseers on high-risk workflows

venturebeat.com Ben Dickson 2025-08-23 10:27:45

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more While enterprises face the challenges of deploying AI agents in critical applications, a new, more pragmatic model is emerging that puts humans back in control as a strategic safeguard against AI failure. One such example is Mixus, a platform that uses a “colleague-in-the-loop” approach to make AI agents reliable for mission-critical work

Topics: agent agents ai enterprise human

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Missing Heritability: Much More Than You Wanted to Know

news.ycombinator.com Scott Alexander 2025-08-23 10:13:00

The Story So Far The mid-20th century was the golden age of nurture. Psychoanalysis, behaviorism, and the spirit of the ‘60s convinced most experts that parents, peers, and propaganda were the most important causes of adult personality. Starting in the 1970s, the pendulum swung the other way. Twin studies shocked the world by demonstrating that most behavioral traits - including socially relevant traits like IQ - were substantially genetic. Typical estimates for adult IQ found it was about 60%

Topics: genes heritability people studies twin

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AlphaGenome: AI for Better Understanding the Genome

news.ycombinator.com Unknown 2025-08-20 15:14:49

Science AlphaGenome: AI for better understanding the genome Share Copy link × Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API. The genome is our cellular instruction manual. It’s the complete set of DNA which guides nearly every part of a living organism, from appearance and function to growth and reproduction. Small variations in a genome’s DNA sequence can alter a

Topics: alphagenome dna model sequence variants

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Jesse Draper’s Halogen Ventures closes $30M Fund III to focus on ‘future of family’

techcrunch.com Dominic-Madori Davis 2025-08-24 03:23:26

In Brief Halogen Ventures closed a $30 million Fund III to invest in early-stage startups building in the “future of family,” as reported first by Fortune. The firm was founded in 2015 by Jesse Draper, the daughter of famed venture capitalist Tim Draper. She explained to Fortune that the fund will focus on the physical and financial health of households. Startups in the care economy have received more investor interest in the past few years after the pandemic, which exacerbated childcare and

Topics: fund halogen health million ventures

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OpenAI’s API lead explains how enterprises are already succeeding with its Agents SDK and Responses API

venturebeat.com Carl Franzen 2025-08-24 11:02:25

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more At VentureBeat’s Transform 2025 conference, Olivier Godement, Head of Product for OpenAI’s API platform, provided a behind-the-scenes look at how enterprise teams are adopting and deploying AI agents at scale. In a 20-minute panel discussion I hosted exclusively with Godement, the former Stripe researcher and current OpenAI API boss unpac

Topics: agents api enterprise godement openai

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DOGE Gets the Green Light to Slash Gun Regulations at ATF

gizmodo.com Aj Dellinger 2025-08-24 15:30:33

Elon Musk may be out of the picture, but the Department of Government Efficiency is still around and being deployed to terrorize the public servants at agencies across the federal government. The latest target: the Bureau of Alcohol, Tobacco, Firearms and Explosives, where DOGE will be tasked with slashing gun restrictions, according to the Washington Post. DOGE staff (those who are left, at least, seeing as high-profile figures like Big Balls have tapped out of the operation) are reportedly be

Topics: agency doge firearms gun post

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NASA Is in Full Meltdown

futurism.com Unknown 2025-08-24 16:08:58

Career NASA officials were seen looking mighty freaked out during a recent town hall event about the agency's dicey future. As Ars Technica's Stephen Clark reports based on a livestream of the town hall — which was not advertised and has since been taken down — acting NASA administrator and career agency official Janet Petro looked like a hostage as she answered questions from staff about the agency's dire standing under president Donald Trump. The hostage-taker in this scenario appears to be

Topics: administrator agency nasa petro trump

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Apple tests if AI assistants can anticipate the consequences of in-app actions

9to5mac.com Marcus Mendes 2025-08-25 07:08:42

As AI agents come closer to taking real actions on our behalf (messaging someone, buying something, toggling account settings, etc.), a new study co-authored by Apple looks into how well do these systems really understand the consequences of their actions. Here’s what they found out. Presented recently at the ACM Conference on Intelligent User Interfaces in Italy, the paper From Interaction to Impact: Towards Safer AI Agents Through Understanding and Evaluating Mobile UI Operation Impacts intro

Topics: actions agents ai ui user

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Graphic artists in China push back on AI and its averaging effect

theverge.com Gus Rick 2025-08-25 11:00:00

Sendi Jia, a designer running her own studio between Beijing, China, and London, England, says she mainly uses AI generators like DALL-E to make fake photos for background panels or websites when her clients don’t have access to real ones. That’s helped clients with limited budgets, but it’s also exposed just how much of the creative process AI can replace. Recently, a potential client working in a university contacted Jia about creating the logo for a new project. Then, they changed their mind.

Topics: ai clients designers generators image

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Business leaders continue to push workers toward daily use of AI

zdnet.com Vala Afshar 2025-08-25 20:00:16

ismagilov/Getty Images Daily AI usage for desk workers has grown by 233% since the beginning of the year, according to Salesforce's latest Slack Workforce Index based on a survey of 5,000 desk workers globally. AI now helps to create a competitive advantage by providing 64% more productivity and 81% more job satisfaction for those who use AI versus colleagues who don't. And the benefits of AI go far beyond task automation. Since November 2024, AI adoption among workers has risen 50%, with 60%

Topics: agents ai daily work workers

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The hidden scaling cliff that’s about to break your agent rollouts

venturebeat.com Marty Swant 2025-08-25 23:33:40

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more Enterprises that want to build and scale agents also need to embrace another reality: agents aren’t built like other software. Agents are “categorically different” in how they’re built, how they operate, and how they’re improved, according to Writer CEO and co-founder May Habib. This means ditching the traditional software development lif

Topics: agents enterprise habib new said

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“My Malformed Bones” – Harry Crews’s Counterlives

news.ycombinator.com Charlie Lee 2025-08-22 15:50:56

Adjust Share One night in early 1941, when Harry Crews was five years old, his father nearly killed his mother with a twelve-gauge shotgun. Looking back almost four decades later, Crews didn’t find that fact particularly exceptional. This was Bacon County, Georgia, where in those days “it was not unusual for a man to shoot at his wife,” as he wrote in his memoir A Childhood: The Biography of a Place. “It was only unusual if he hit her.” Crews and his older brother heard the shot, which blew the

Topics: car crews eugene herman life

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"My Malformed Bones" Harry Crews's Counterlives

news.ycombinator.com Charlie Lee 2025-08-22 20:50:56

Adjust Share One night in early 1941, when Harry Crews was five years old, his father nearly killed his mother with a twelve-gauge shotgun. Looking back almost four decades later, Crews didn’t find that fact particularly exceptional. This was Bacon County, Georgia, where in those days “it was not unusual for a man to shoot at his wife,” as he wrote in his memoir A Childhood: The Biography of a Place. “It was only unusual if he hit her.” Crews and his older brother heard the shot, which blew the

Topics: car crews eugene herman life

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Changing one gene can restore some tissue regeneration to mice

arstechnica.com Unknown 2025-08-26 03:09:26

Regeneration is a trick many animals, including lizards, starfish, and octopuses, have mastered. Axolotls, a salamander species originating in Mexico, can regrow pretty much everything from severed limbs, through eyes and parts of brain, to the spinal cord. Mammals, though, have mostly lost this ability somewhere along their evolutionary path. Regeneration persisted, in a limited number of tissues, in just a few mammalian species like rabbits or goats. “We were trying to learn how certain anima

Topics: mice rabbits regenerating regeneration wang

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Get paid faster: How Intuit’s new AI agents help businesses get funds up to 5 days faster and save 12 hours a month with autonomous workflows

venturebeat.com Sean Michael Kerner 2025-08-26 06:00:00

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more Intuit has been on a journey over the last several years with generative AI, incorporating the technology as part of its services at QuickBooks, Credit Karma,Turbotax and Mailchimp. Today the company is taking the next step with a series of AI agents that go beyond that to transform how small and mid-market businesses operate. These new a

Topics: agent agents ai business intuit

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Lessons learned from agentic AI leaders reveal critical deployment strategies for enterprises

venturebeat.com Sean Michael Kerner 2025-08-26 06:07:32

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more Companies are rushing AI agents into production — and many of them will fail. But the reason has nothing to do with their AI models. On day two of VB Transform 2025, industry leaders shared hard-won lessons from deploying AI agents at scale. A panel moderated by Joanne Chen, general partner at Foundation Capital, included Shawn Malhotra,

Topics: agents ai companies customer testing

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AlphaGenome: AI for better understanding the genome

news.ycombinator.com Unknown 2025-08-26 00:16:00

Science AlphaGenome: AI for better understanding the genome Share Copy link × Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API. The genome is our cellular instruction manual. It’s the complete set of DNA which guides nearly every part of a living organism, from appearance and function to growth and reproduction. Small variations in a genome’s DNA sequence can alter a

Topics: alphagenome dna model sequence variants

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What enterprise leaders can learn from LinkedIn’s success with AI agents

venturebeat.com Taryn Plumb 2025-08-26 11:15:00

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more AI agents are one of the hottest topics in tech right now — but how many enterprises have actually deployed and are actively using them? LinkedIn says it has with its LinkedIn hiring assistant. Going beyond its popular recommender systems and AI-powered search, the company’s AI agent sources and recruits job candidates through a simple na

Topics: agent agents ai linkedin said

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Analysis: During a town hall NASA officials on stage looked like hostages

arstechnica.com Unknown 2025-08-26 08:47:14

The four people at the helm of America's space agency held a town hall meeting with employees Wednesday, fielding questions about downsizing, layoffs, and proposed budget cuts that threaten to undermine NASA's mission and prestige. Janet Petro, NASA's acting administrator, addressed questions from an auditorium at NASA Headquarters in Washington, DC. She was joined by Brian Hughes, the agency's chief of staff, a political appointee who was formerly a Florida-based consultant active in city poli

Topics: agency budget employees nasa percent

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Some bits on malloc(0) in C being allowed to return NULL

news.ycombinator.com Unknown 2025-08-25 17:15:11

You're using a tool with a too-generic User-Agent You're probably reading this page because you've attempted to access some part of my blog (Wandering Thoughts) or CSpace, the wiki thing it's part of. Unfortunately whatever you're using to do so has a HTTP User-Agent header value that is too generic or otherwise excessively suspicious. Unfortunately, as of early 2025 there's a plague of high volume crawlers (apparently in part to gather data for LLM training) that behave like this. To reduce th

Topics: agent generic http user using

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Google DeepMind Releases AlphaGenome

news.ycombinator.com Unknown 2025-08-27 01:16:00

Science AlphaGenome: AI for better understanding the genome Share Copy link × Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API. The genome is our cellular instruction manual. It’s the complete set of DNA which guides nearly every part of a living organism, from appearance and function to growth and reproduction. Small variations in a genome’s DNA sequence can alter a

Topics: alphagenome dna model sequence variants

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DOGE’d Federal Employees Are Getting Hit With Bills for Phantom Health Coverage

gizmodo.com Ellyn Lapointe 2025-08-27 03:35:49

The National Oceanic and Atmospheric Administration (NOAA) has spent the last six months in turmoil, with the Trump administration drastically reducing the agency’s nationwide workforce. To make matters worse, the federal government is now demanding money from some former employees. Three ex-NOAA staffers who were fired, rehired, then fired again this spring received notices from the federal government stating they owed a debt for healthcare coverage. The letters, shared exclusively with NBC Ne

Topics: administration agency employees noaa told

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watchOS 26 has these hardware requirements for Apple Intelligence

9to5mac.com Ryan Christoffel 2025-08-27 08:11:44

watchOS 26 is the Apple Watch’s next major hardware update, and it includes several Apple Intelligence-powered features. Here are the hardware requirements to get Apple Intelligence on your Watch. New AI features on Apple Watch each have unique requirements Last year when Apple Intelligence first launched, it was exclusive to iPhone, iPad, and Mac. Since then, Vision Pro has been added. In watchOS 26, Apple is bringing AI features to the Apple Watch too. But when it comes to hardware compatib

Topics: apple features intelligence iphone watch

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DirecTV's New $20 Streaming Bundle Is Tailor-Made for Your Kids

cnet.com See Full Bio 2025-08-27 06:02:00

After introducing Genre Packs this past February, DirecTV is launching a new streaming option called MyKids for $20 a month, the TV provider announced Thursday. The offering is aimed at cord-cutters and joins the Genre Pack lineup as an affordable family-friendly package with live channels from Paramount, Disney, Warner Bros. Discovery and a Disney Plus subscription at no extra charge. Signing up for the MyKids pack doesn't require a satellite subscription, and you get access to a selection of

Topics: channels disney genre network paramount

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Learnings from building AI agents

news.ycombinator.com Unknown 2025-08-27 09:45:04

How we made our AI code reviewer stop being so noisy I’m Paul, cofounder of cubic —an "AI-native GitHub." One of our core features is an AI code review agent that performs an initial review pass, catching bugs, anti-patterns, duplicated code, and similar issues in pull requests. When we first released this agent back in April, the main feedback we got was straightforward: it was too noisy. Even small PRs often ended up flooded with multiple low-value comments, nitpicks, or outright false posi

Topics: agent ai comments issues reasoning

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AMD demo shows procedural generation slashing VRAM use from 35 GB to just 51 KB

techspot.com Daniel Sims 2025-08-27 14:51:00

Why it matters: Managing graphics memory has become one of the most pressing challenges facing the realm of real-time 3D rendering. As visuals become more detailed, the amount of VRAM required for modern high-end games is pushing against what average customers can afford. AMD and Nvidia are currently developing remedies to the issue, which involve shifting certain rendering tasks from memory to the GPU. A new research paper from AMD explains how procedurally generating certain 3D objects in rea

Topics: generation graphs memory vram work

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Latest Tech News

Scientists Launch Wild New Project to Build a Human Genome From Scratch

Hollywood’s pivot to AI video has a prompting problem

From hallucinations to hardware: Lessons from a real-world computer vision project gone sideways

The AI Backlash Keeps Growing Stronger

AI agents are hitting a liability wall. Mixus has a plan to overcome it using human overseers on high-risk workflows

Missing Heritability: Much More Than You Wanted to Know

AlphaGenome: AI for Better Understanding the Genome

Jesse Draper’s Halogen Ventures closes $30M Fund III to focus on ‘future of family’

OpenAI’s API lead explains how enterprises are already succeeding with its Agents SDK and Responses API

DOGE Gets the Green Light to Slash Gun Regulations at ATF

NASA Is in Full Meltdown

Apple tests if AI assistants can anticipate the consequences of in-app actions

Graphic artists in China push back on AI and its averaging effect

Business leaders continue to push workers toward daily use of AI

The hidden scaling cliff that’s about to break your agent rollouts

“My Malformed Bones” – Harry Crews’s Counterlives

"My Malformed Bones" Harry Crews's Counterlives

Changing one gene can restore some tissue regeneration to mice

Get paid faster: How Intuit’s new AI agents help businesses get funds up to 5 days faster and save 12 hours a month with autonomous workflows

Lessons learned from agentic AI leaders reveal critical deployment strategies for enterprises

AlphaGenome: AI for better understanding the genome

What enterprise leaders can learn from LinkedIn’s success with AI agents

Analysis: During a town hall NASA officials on stage looked like hostages

Some bits on malloc(0) in C being allowed to return NULL

Google DeepMind Releases AlphaGenome

DOGE’d Federal Employees Are Getting Hit With Bills for Phantom Health Coverage

watchOS 26 has these hardware requirements for Apple Intelligence

DirecTV's New $20 Streaming Bundle Is Tailor-Made for Your Kids

Learnings from building AI agents

AMD demo shows procedural generation slashing VRAM use from 35 GB to just 51 KB

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