GoKawiil
Efficient and precise programmable DNA knock-in without double-strand breaks
(feeds.nature.com)
1.
2.
Precise DNA base editing using AlphaFold3-based contact modelling
(feeds.nature.com)
3.
CRISPR gets a power boost from AI-designed ‘molecular scissors’
(feeds.nature.com)
4.
Heat-triggered phospholipid flipping stabilizes plasma membrane fluidity
(feeds.nature.com)
5.
Small-molecule modulation of β-arrestins
(feeds.nature.com)
6.
Prime assembly with linear DNA donors enables large genomic insertions
(feeds.nature.com)
7.
Quadruple pegRNA enables programmable and efficient large genomic insertion
(feeds.nature.com)
8.
Molecular basis for methylation-sensitive editing by Cas9
(feeds.nature.com)
9.
Clinical trial shows gene editing works for β-Thalassaemia, too
(arstechnica.com)
10.
11.
Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity
(feeds.nature.com)
12.
Daily briefing: Static electricity is still a mystery — here’s what we know
(feeds.nature.com)
13.
CRISPR makes enhanced cancer-fighting immune cells inside mice
(feeds.nature.com)
14.
Synthetic circuits for cell ratio control
(feeds.nature.com)
15.
In vivo site-specific engineering to reprogram T cells
(feeds.nature.com)
16.
A Visual Guide to Genome Editors
(news.ycombinator.com)