GoKawiil
Cohesin reshapes replication fork contacts to aid fork slowing and reversal
(feeds.nature.com)
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Efficient and precise programmable DNA knock-in without double-strand breaks
(feeds.nature.com)
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Precise DNA base editing using AlphaFold3-based contact modelling
(feeds.nature.com)
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CRISPR gets a power boost from AI-designed ‘molecular scissors’
(feeds.nature.com)
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Heat-triggered phospholipid flipping stabilizes plasma membrane fluidity
(feeds.nature.com)
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Small-molecule modulation of β-arrestins
(feeds.nature.com)
9.
Prime assembly with linear DNA donors enables large genomic insertions
(feeds.nature.com)
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Quadruple pegRNA enables programmable and efficient large genomic insertion
(feeds.nature.com)
11.
Molecular basis for methylation-sensitive editing by Cas9
(feeds.nature.com)
12.
Clinical trial shows gene editing works for β-Thalassaemia, too
(arstechnica.com)
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Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity
(feeds.nature.com)
15.
Daily briefing: Static electricity is still a mystery — here’s what we know
(feeds.nature.com)
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CRISPR makes enhanced cancer-fighting immune cells inside mice
(feeds.nature.com)
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Synthetic circuits for cell ratio control
(feeds.nature.com)
18.
In vivo site-specific engineering to reprogram T cells
(feeds.nature.com)
19.
A Visual Guide to Genome Editors
(news.ycombinator.com)