GoKawiil
Tech News
A preprint study indicates that hearts transplanted into younger individuals may undergo biological rejuvenation, while those placed in older bodies exhibit signs of accelerated aging. The research, posted on bioRxiv, is yet to undergo peer review. This suggests that the biological age of a heart can adapt to its new host's age.
Researchers led by Jesse Poganik at Harvard University report, in a bioRxiv preprint not yet peer-reviewed, that young donor hearts age faster once placed in older recipients, while older hearts appear to become biologically younger when transplanted into younger bodies. The team reached this conclusion by grafting extra hearts between mice of different ages and analyzing DNA methylation patterns linked to cellular ageing, and note similar patterns were examined in human transplant tissue.
A preprint analyzing nearly 900 recipients of NIH K career-development awards found that successful early-career researchers typically had a median of three mentors, with some reporting as many as 15. These mentors served distinct functions: research mentors mainly helped with publications and grant writing, while other mentors provided professional introductions, skill-building, or emotional support.