Tenk10k - GoKawiil

TenK10K study links 1,042 blood samples to chromatin accessibility atlas

Researchers built a single-cell chromatin accessibility atlas using blood samples from 1,042 individuals drawn from the TenK10K phase I cohort, combining the Tasmanian Ophthalmic Biobank, BioHeart and Liquid Biopsy Biobank cohorts. The team used 10X Genomics single-cell ATAC-seq technology on 952 of these donors to map genetic variants influencing chromatin accessibility, a step toward understanding disease risk at the cellular level.

nature.com · 2026-10-28

TenK10K project maps gene-regulation variants across 50 million single cells

Researchers published the first-phase results of TenK10K, an expansion of the earlier OneK1K study, in Nature. The project combines single-cell RNA sequencing with other molecular profiling methods to catalogue genetic variants affecting gene expression across cell types, drawing on a planned cohort of 10,000 diverse individuals.

nature.com · 2026-10-28