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Newborns have elevated levels of a biomarker for Alzheimer's

news.ycombinator.com University Of Gothenburg 2025-11-02 10:30:37

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: Credit: Brain Communications (2025). DOI: 10.1093/braincomms/fcaf221 Newborn babies and patients with Alzheimer's disease share an unexpected biological trait: elevated levels of a well-known biomarker for Alzheimer's, as shown in a study led by researchers at the University of Gothenburg and published in Brain Comm

Topics: alzheimer brain levels newborns tau217

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Raleigh One e-bike launches with VanMoof DNA

theverge.com Thomas Ricker 2025-11-03 03:00:00

The Raleigh One e-bike is now official after The Verge first published details of it last week. It was developed for the Accell Group’s Raleigh brand with help from VanMoof’s cofounders, Ties and Taco Carlier, according to my sources. The announcement never mentions their involvement, which could be viewed as good or bad — good if you view the brothers as innovators, bad if you got burned during the VanMoof bankruptcy or the turmoil that preceded it. I think everyone can agree, however, that th

Topics: accell bike new raleigh vanmoof

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Judge Says Requiring ChatGPT to Save Chat Logs Is Not a ‘Mass Surveillance Program’

gizmodo.com Aj Dellinger 2025-11-03 15:20:25

OpenAI and some of its users have objected to a court order that requires the company to indefinitely maintain all of ChatGPT’s chat logs as part of an ongoing copyright lawsuit, claiming that holding onto such records amounts to a “nationwide mass surveillance program.” The court was not moved. Judge Ona Wang, who initially issued the order to retain all data from the popular chatbot, rejected multiple requests to overturn the decision—though OpenAI has vowed to continue to fight the order, acc

Topics: chatgpt company logs order surveillance

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How a grad student got LHC data to play nice with quantum interference

arstechnica.com Unknown 2025-11-05 21:00:08

Measurements at the Large Hadron Collider have been stymied by one of the most central phenomena of the quantum world. But now, a young researcher has championed a new method to solve the problem using deep neural networks. The Large Hadron Collider is one of the biggest experiments in history, but it’s also one of the hardest to interpret. Unlike seeing an image of a star in a telescope, saying anything at all about the data that comes out of the LHC requires careful statistical modeling. “If

Topics: data interference lhc new seeing

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Best Internet Providers in Anaheim, California

cnet.com See Full Bio 2025-11-05 20:31:00

What is the best internet provider in Anaheim? AT&T Fiber is CNET's top pick for the best internet service provider in Anaheim. The internet service provider is the best option for most households in the city because of its fast, symmetrical speeds that come with straightforward plan terms and reasonable pricing. Not every address in Anaheim is served by AT&T Fiber. For those outside the coverage area, options like Spectrum or T-Mobile Home Internet are also solid picks, depending on what’s ava

Topics: anaheim fiber internet plan spectrum

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We’ve had a Denisovan skull since the 1930s—only nobody knew

news.ycombinator.com Unknown 2025-11-01 11:42:58

A 146,000-year-old skull from Harbin, China, belongs to a Denisovan, according to a recent study of proteins preserved inside the ancient bone. The paleoanthropologists who studied the Harbin skull in 2021 declared it a new (to us) species, Homo longi. But the Harbin skull still contains enough of its original proteins to tell a different story: A few of them matched specific proteins from Denisovan bones and teeth, as encoded in Denisovan DNA. So Homo longi was a Denisovan all along, and thank

Topics: denisovan dna harbin proteins skull

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Israel urges citizens to turn off home cameras as Iran hacks surveillance systems

techspot.com Skye Jacobs 2025-11-05 14:10:00

Cutting corners: As tensions between Israel and Iran escalate, Israeli authorities are urging citizens to take an unusual but crucial step: turn off their home security cameras or change their passwords. The warning comes amid growing evidence that Iran is actively attempting to tap into private surveillance devices across Israel to gather intelligence for military operations. In the aftermath of recent Iranian missile strikes on Tel Aviv, concerns about the vulnerability of internet-connected

Topics: cameras israel security surveillance systems

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US tech czar warns China is only two years behind in semiconductor and chip design

techspot.com Skye Jacobs 2025-11-05 09:57:00

TL;DR: White House technology adviser David Sacks has raised concerns that China is rapidly narrowing the gap with the United States in semiconductor design, estimating the difference is now just one and a half to two years. In a recent interview with Bloomberg, Sacks said Chinese companies, especially Huawei, have become adept at finding ways around US restrictions on advanced chip technology. According to Sacks, Huawei is making swift progress in chip design and could soon begin exporting its

Topics: ai chinese chip huawei sacks

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Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s

wired.com Emily Mullin 2025-11-05 08:01:00

Eli Lilly’s daily anti-obesity pill orforglipron appears to be as good at spurring weight loss and lowering blood sugar in diabetes patients as popular injectable GLP-1 drugs like Ozempic, according to new data from a Phase 3 trial. The results were announced today at the annual meeting of the American Diabetes Association and published in the New England Journal of Medicine. Eli Lilly is the maker of the blockbuster GLP-1 drug tirzepatide, approved as Mounjaro for type 2 diabetes and Zepbound

Topics: drugs glp orforglipron pill weight

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Sega mistakenly reveals sales numbers of popular games

news.ycombinator.com Sal Romano 2025-11-05 05:23:01

Total sales numbers for various SEGA and ATLUS titles including Like a Dragon: Infinite Wealth, Persona 3 Reload, Sonic Frontiers, Shin Megami Tensei V, and Persona 5 Royal were mistakenly revealed in a SEGA SAMMY Management Meeting 2025 presentation published on June 18. The sales numbers, which appear on page 25 of the presentation, are hidden behind a grey block. However, due to the way the PDF file is formatted, simply highlighting the page reveals the presence of text, which can be copied

Topics: megami persona sales shin tensei

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VanMoof is back with a new custom e-bike and rebooted repair network

techcrunch.com Rebecca Bellan 2025-11-07 05:04:00

Dutch e-bike startup VanMoof is back two years after bankruptcy with its first model designed under new leadership. And despite past criticism that VanMoof’s over-reliance on custom parts led to the company’s downfall, the S6 sticks to the brand’s signature bespoke design. Today, VanMoof is betting that higher-quality custom parts, alongside a more robust servicing network, will allow it to stay true to its design-forward, tech-heavy core, while avoiding the repair and servicing pitfalls that c

Topics: bike new s6 vanmoof wertheimer

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Elden Ring Nightreign is getting even harder bosses

theverge.com Jay Peters 2025-11-09 15:32:55

is a news editor covering technology, gaming, and more. He joined The Verge in 2019 after nearly two years at Techmeme. The bosses in Elden Ring Nightreign are already pretty tough. But if you’ve gotten good and need a harder challenge, you’ll be able to take on “Everdark Sovereigns,” which are more difficult versions of the game’s Nightlord foes you face to conclude a run. “These limited-time versions of the Nightlords are extremely challenging and pose an even greater threat to the Nightfare

Topics: added everdark ll new sovereign

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Toxic Proteins for Drug Discovery

news.ycombinator.com Asimov Press 2025-11-09 06:04:22

Noah Whiteman, professor of evolutionary biology at UC Berkeley, writes about how toxins are repurposed into medicines for Issue 06. Whiteman’s recent book is called “Most Delicious Poison.” Ella Watkins-Dulaney for Asimov Press. When you hear the word "poison," perhaps you picture a Victorian-era cobalt bottle labeled "NOT TO BE TAKEN" or the iconic pictogram of a leering skull and crossbones. What probably does not come to mind, however, are the dried white beans in your kitchen pantry, the

Topics: cells peptides proteins toxic toxin

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Bulk Up: The 8 Best Foods for Building Muscle

cnet.com See Full Bio 2025-11-11 09:00:00

Spending time at the gym isn't the only thing that can help you build muscle. While putting in time at the gym is the first step, eating well also makes a major difference. Building muscle requires proper nutrition to recover from workouts, and starving yourself isn't going to cut it. If you aren't eating right, you might not see the results you've been working for. That's where food comes in. A smart, balanced diet-especially one packed with high-quality protein, can make a major difference in

Topics: building diet food muscle protein

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Someone Stole 2,810 Nintendo Switch 2s and I Think I Know Who It Was

gizmodo.com James Pero 2025-11-11 20:30:33

The Switch 2 is in pretty high demand. Like, so high that it’s leading to cartoonish heist levels of high. According to police in Arapahoe County, Colo., 2,810 Switch 2s were stolen out of a truck earlier this month. A truck driver reportedly discovered the missing consoles at a pre-inspection truck stop after noticing the trailer had been broken into en route to a GameStop in Texas. According to 9NBC news, which first reported the heist, multiple pallets worth of consoles were stolen, and, as t

Topics: big console consoles heist police

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DOJ seizes record $225 million in crypto tied to global 'pig butchering' scams

cnbc.com Mackenzie Sigalos 2025-11-12 05:51:16

The Justice Department announced Wednesday the largest-ever U.S. seizure of cryptocurrency linked to so-called "pig butchering" scams that have cost victims billions globally. Federal prosecutors filed a civil forfeiture action targeting more than $225 million in cryptocurrency traced to a sprawling web of fraudulent investment platforms. Victims were tricked into believing they were investing in legitimate crypto ventures, only to be scammed by criminal networks often operating overseas. "Thi

Topics: crypto cryptocurrency investment seizure victims

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We’ve had a Denisovan skull since the 1930s—only nobody knew

arstechnica.com Unknown 2025-11-12 20:00:37

A 146,000-year-old skull from Harbin, China, belongs to a Denisovan, according to a recent study of proteins preserved inside the ancient bone. The paleoanthropologists who studied the Harbin skull in 2021 declared it a new (to us) species, Homo longi. But the Harbin skull still contains enough of its original proteins to tell a different story: A few of them matched specific proteins from Denisovan bones and teeth, as encoded in Denisovan DNA. So Homo longi was a Denisovan all along, and thank

Topics: denisovan dna harbin proteins skull

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Leica is launching its own 35mm film

theverge.com Dominic Preston 2025-11-13 05:43:20

is a news editor with over a decade’s experience in journalism. He previously worked at Android Police and Tech Advisor. Leica has announced the first 35mm film produced under its own name, Monopan 50. It’s an ultra-fine grain black-and-white film, and will cost $10 per 36-exposure roll when it goes on sale on August 21st. Leica says that the new film is produced in Germany, though wouldn’t name a manufacturer when asked. The specs, right down to every curve of the spectral sensitivity chart,

Topics: 50 film leica monopan sensitivity

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VanMoof’s co-founders have a new e-bike coming from Raleigh

theverge.com Thomas Ricker 2025-11-13 05:51:04

is a deputy editor and Verge co-founder with a passion for human-centric cities, e-bikes, and life as a digital nomad. He’s been a tech journalist for 20 years. Ties and Taco Carlier, who founded VanMoof as an alternative to Big Bike, are working for Accell Group, the Dutch cycling giant responsible for over a dozen bicycle brands including Batavus, Sparta, Carqon, and Raleigh. According to multiple sources, the first e-bike, developed for the Raleigh brand and pictured above, is nearing comple

Topics: accell bike group raleigh vanmoof

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Paddle settles for $5 million over facilitating tech support scams

bleepingcomputer.com Unknown 2025-11-13 10:14:18

Paddle.com and its U.S. subsidiary will pay $5 million to settle Federal Trade Commission (FTC) allegations that the company facilitated deceptive tech-support schemes that harmed many U.S. consumers, including older adults. Paddle, a UK-based payment processor, offers payments, tax handling, compliance, and checkout infrastructure for software and digital product sellers by acting as a "merchant of record." According to the FTC, Paddle failed to perform adequate screening and fraud prevention

Topics: deceptive ftc paddle reimage software

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Incant – add magic spells to your code

news.ycombinator.com Unknown 2025-11-11 06:33:34

// incant looks in your env array for an OPENAI_API_KEY & other vars // easy for end users to configure for your cli const { , } = createIncant ( { env Deno . env . toObject ( ) , } ) ;

Topics: array cli configure createincant env

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The Interpretable AI playbook: What Anthropic’s research means for your enterprise LLM strategy

venturebeat.com Ross Teixeira 2025-11-14 00:01:08

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more Anthropic CEO Dario Amodei made an urgent push in April for the need to understand how AI models think. This comes at a crucial time. As Anthropic battles in global AI rankings, it’s important to note what sets it apart from other top AI labs. Since its founding in 2021, when seven OpenAI employees broke off over concerns about AI safety,

Topics: ai amodei anthropic interpretability models

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Jason Momoa’s Kid Was Just Cast in ‘Dune 3’

gizmodo.com Germain Lussier 2025-11-14 05:00:41

Just when you thought one Momoa starring in a Dune movie was a big deal, a whole second Momoa is entering the conversation. We already knew Jason Momoa was expected to return for Denis Villeneuve’s third and final Dune film, Dune Messiah, whenever it comes to be. But now, his son, Nakoa-Wolf Momoa has joined the cast along with Silo’s Ida Brooke as the kids of Paul Atreides (Timothée Chalamet) and Chani (Zendaya). Deadline broke the news of the casting, which is the first public movement on the

Topics: atreides deadline dune messiah momoa

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Toy-maker Mattel accused of planning “reckless” AI social experiment on kids

arstechnica.com Unknown 2025-11-14 20:22:43

After Mattel and OpenAI announced a partnership that would result in an AI product marketed to kids, a consumer rights advocacy group is warning that the collaboration may endanger children. It remains unclear what shape Mattel's first-ever AI product will take. But on Tuesday, Public Citizen co-President Robert Weissman issued a statement urging more transparency so that parents can prepare for potential risks. Weissman is particularly concerned that ChatGPT-fueled toys could hurt kids in unkn

Topics: ai children mattel toys weissman

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Surgery Still Beats Ozempic and Other GLP-1 Drugs in Real-World Weight Loss Study

gizmodo.com Ed Cara 2025-11-15 05:05:43

When it comes to weight loss, surgery still reigns supreme. Research out today shows that people undergoing bariatric surgery tend to lose significantly more weight than people taking the newest, most effective GLP-1 medications for obesity. Scientists at New York University conducted the study, which analyzed real-world data from obesity patients. People who received surgery lost five times more weight over a two year span on average than those who were prescribed a GLP-1 drug, they found. The

Topics: drugs glp people surgery weight

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Taiwan joins chip war escalation, blocks exports to Huawei and SMIC

techspot.com Skye Jacobs 2025-11-16 05:46:00

What just happened? Taiwan has imposed sweeping new export controls on two of China's most critical technology firms, Huawei Technologies and SMIC, thereby escalating a high-stakes battle over the future of advanced semiconductors and artificial intelligence. The move, announced by Taiwan's Ministry of Economic Affairs and approved by the International Trade Administration, places both companies on the strategic high-tech commodities entity list, a roster that includes organizations such as the

Topics: controls export huawei smic taiwan

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A New Obesity Pill May Burn Fat Without Suppressing Appetite

wired.com Emily Mullin 2025-11-19 09:00:00

An experimental obesity pill that works in a different way from the wildly popular Ozempic may help people lose weight, according to results from a small, preliminary human trial. Ozempic and other GLP-1 drugs reduce food intake by stimulating a feeling of fullness. They act on the brain to promote satiety and on the gut to slow the movement of food through the stomach, helping people feel full longer. As a result, people on the drugs lose weight because they eat less. But a new drug may be ab

Topics: creatine drug heat people weight

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The WIRED Guide to Protecting Yourself From Government Surveillance

wired.com Andy Greenberg 2025-11-19 10:00:00

The Trump administration has ordered Immigration and Customs Enforcement agents to carry out sweeping raids, deporting thousands of immigrants, often without due process. It has targeted left-leaning foreign students and entire universities, canceling visas and threatening to withhold federal funding. United States Supreme Court appointments from the previous Trump administration have resulted in decisions that enabled roughly half of US states to severely restrict or ban abortions. And Trump’s

Topics: data privacy security surveillance trump

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Taiwan blacklists China's Huawei and SMIC, further aligning with U.S. trade policy

cnbc.com Dylan Butts 2025-11-19 10:55:58

The U.S. has placed major chip export restrictions on Huawei and Chinese firms over the past few years. This has cut off companies' access to critical semiconductors. Taiwan has added China's Huawei and SMIC to its trade blacklist in a move that further aligns it with U.S. trade policy and comes amid growing tensions with Beijing. The two leading Chinese chip firms have been put on Taiwan's "Strategic High-Tech Commodities Entity List," along with many of their international subsidiaries. Tai

Topics: export huawei smic taiwan trade

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DARPA program sets distance record for power beaming

news.ycombinator.com Unknown 2025-11-19 02:40:40

In a series of recent tests in New Mexico, the Persistent Optical Wireless Energy Relay (POWER) program achieved several new records for transmitting power over distance. The team recorded more than 800 watts of power delivered during a 30-second transmission from a laser 8.6 kilometers (5.3 miles) away. Over the course of the test campaign, more than a megajoule of energy was transferred. Previously, the greatest reported distance records for an appreciable amount of optical power (>1 microwat

Topics: distance energy power receiver test

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Latest Tech News

Newborns have elevated levels of a biomarker for Alzheimer's

Raleigh One e-bike launches with VanMoof DNA

Judge Says Requiring ChatGPT to Save Chat Logs Is Not a ‘Mass Surveillance Program’

How a grad student got LHC data to play nice with quantum interference

Best Internet Providers in Anaheim, California

We’ve had a Denisovan skull since the 1930s—only nobody knew

Israel urges citizens to turn off home cameras as Iran hacks surveillance systems

US tech czar warns China is only two years behind in semiconductor and chip design

Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s

Sega mistakenly reveals sales numbers of popular games

VanMoof is back with a new custom e-bike and rebooted repair network

Elden Ring Nightreign is getting even harder bosses

Toxic Proteins for Drug Discovery

Bulk Up: The 8 Best Foods for Building Muscle

Someone Stole 2,810 Nintendo Switch 2s and I Think I Know Who It Was

DOJ seizes record $225 million in crypto tied to global 'pig butchering' scams

We’ve had a Denisovan skull since the 1930s—only nobody knew

Leica is launching its own 35mm film

VanMoof’s co-founders have a new e-bike coming from Raleigh

Paddle settles for $5 million over facilitating tech support scams

Incant – add magic spells to your code

The Interpretable AI playbook: What Anthropic’s research means for your enterprise LLM strategy

Jason Momoa’s Kid Was Just Cast in ‘Dune 3’

Toy-maker Mattel accused of planning “reckless” AI social experiment on kids

Surgery Still Beats Ozempic and Other GLP-1 Drugs in Real-World Weight Loss Study

Taiwan joins chip war escalation, blocks exports to Huawei and SMIC

A New Obesity Pill May Burn Fat Without Suppressing Appetite

The WIRED Guide to Protecting Yourself From Government Surveillance

Taiwan blacklists China's Huawei and SMIC, further aligning with U.S. trade policy

DARPA program sets distance record for power beaming

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