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Breakthrough cancer test predicts whether chemotherapy will work

news.ycombinator.com Sarah Knapton 2025-09-01 11:11:03

A breakthrough test can successfully predict whether chemotherapy will work so patients can avoid needless side effects. The test, developed by the University of Cambridge, looks at the structure of tumour DNA and forecasts whether it will resist treatment. It was piloted using data from 840 patients with different types of cancer and found that it could help spot whether treatment was likely to fail for ovarian, prostate and breast cancers. James Brenton, a professor of ovarian cancer medici

Topics: cancer chemotherapy effects test treatment

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macOS Tahoe 26 beta 2 includes toggle to restore menu bar background

9to5mac.com Zac Hall 2025-09-02 05:03:55

Apple has added a new toggle to show the menu bar background in macOS Tahoe 26 beta 2. The option was added after beta 1 arrived with no menu bar background and no toggle to restore it. The new option is available in Settings > Menu Bar > Show menu bar background. Currently off by default, the toggle works as advertised by simply restoring the frosted layer of menu bar background across the width of your Mac display. The toggle does not affect the placement of menu bar items or text. Apple rem

Topics: background bar mac menu toggle

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Mattress Encasement vs. Mattress Protector

wired.com Julia Forbes 2025-09-02 05:02:00

Here's a hard truth: People are gross. Even the cleanliest among us cannot prevent the things that permeate a mattress nightly, oftentimes without us even knowing. This includes things like dandruff, dead skin, dust mites, sweat, and even in accidental cases, urine and blood. Have the “ick” yet? Now imagine the worst comes to pass, and you've got to contend with now cleaning your mattress to remove these things as best as you can. To that end, protecting your mattress shouldn’t even be a questi

Topics: bed encasement just like mattress

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Launch HN: Reducto Studio (YC W24) – Build accurate document pipelines, fast

news.ycombinator.com Unknown 2025-09-02 16:30:33

Hi HN! We’re Adit and Raunak, co-founders of Reducto (YC W24, https://reducto.ai ). Reducto turns unstructured documents (e.g., PDFs, scans, spreadsheets) into structured data. This data can then be used for retrieval, passed into LLMs, or used elsewhere downstream. We started Reducto when we realized that so many of today’s AI applications require good quality data. Everyone knows that good inputs lead to better outputs, but 80% of the world’s data is still trapped inside of things like messy

Topics: data document iterate reducto studio

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DHEA-S hormone linked to shorter lifespan in men, but not women

news.ycombinator.com The City University Of New York 2025-09-02 21:04:41

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: Credit: Pixabay/CC0 Public Domain A new genetic study suggests that higher levels of the hormone dehydroepiandrosterone sulfate (DHEA-s) are associated with a shorter lifespan in men, but show no significant effect on the lifespan of women. The research, led by CUNY SPH Professor Mary Schooling, used a Mendelian ra

Topics: blood dhea lifespan men pressure

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Hinge is planning its own mobile payment system to avoid App Store fees

theverge.com Jay Peters 2025-09-03 01:00:00

is a news editor covering technology, gaming, and more. He joined The Verge in 2019 after nearly two years at Techmeme. As part of his appearance on the Decoder podcast, Hinge co-founder and CEO Justin McLeod says that the company would like to introduce an alternative payment service by the end of this year. With a Hinge-run alternative payment service, Apple won’t be able to take a cut of any purchases, and that “changes the equation” for Hinge on “many fronts,” according to McLeod. Not only

Topics: apple hinge match payment service

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Sailing the fjords like the Vikings yields unexpected insights

arstechnica.com Unknown 2025-09-03 04:52:43

Experimental archaeologist Greer Jarrett of Lund University in Sweden has been sailing in the footsteps of Vikings for the last three years. If you want to learn more about how and where the Vikings sailed, making the journey through the fjords yourself in replica boats is a practical, hands-on approach to achieving that end. Greer Jarrett, an archaeologist at Lund University in Sweden, has spent the last three years doing just that, sailing more than 5,000 kilometers along known Viking trade r

Topics: boats did experimental jarrett university

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Real-world performance comparison of ebtree/cebtree/rbtree

news.ycombinator.com Willy Tarreau 2025-09-03 06:07:29

Brain dumps. Reports about experiments, ideas, and various stuff that's more useful on the net than written on paper stacked on my desk.

Topics: brain desk dumps experiments ideas

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This archaeologist built a replica boat to sail like the Vikings

arstechnica.com Unknown 2025-09-03 09:52:43

Experimental archaeologist Greer Jarrett of Lund University in Sweden has been sailing in the footsteps of Vikings for the last three years. If you want to learn more about how and where the Vikings sailed, making the journey through the fjords yourself in replica boats is a practical, hands-on approach to achieving that end. Greer Jarrett, an archaeologist at Lund University in Sweden, has spent the last three years doing just that, sailing more than 5,000 kilometers along known Viking trade r

Topics: boats did experimental jarrett university

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Book review: Surveillance & privacy

technologyreview.com Bryan Gardiner 2025-09-03 17:00:00

Means of Control: How the Hidden Alliance of Tech and Government Is Creating a New American Surveillance State Byron Tau CROWN, 2024 Midway through his book, Tau, an investigative journalist, recalls meeting with a disgruntled former employee of a data broker—a shady company that collects, bundles, and sells your personal data to other (often shadier) third parties, including the government. This ex-employee had managed to make off with several gigabytes of location data representing the preci

Topics: control data government means tau

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OpenAI and Jony Ive remove ‘io’ branding mentions over trademark lawsuit

9to5mac.com Marcus Mendes 2025-09-03 15:37:10

If you recently looked up but couldn’t find OpenAI’s announcement video about its flashy partnership with Jony Ive, you are not alone. OpenAI has quietly pulled down the original blog post and the accompanying nine-minute video, just weeks after touting the $6.5 billionsc deal as a landmark step toward building new AI hardware. Here’s what happened. The deal is still happening, just with a bit less branding According to a statement given to The Verge, OpenAI says the content was taken offline

Topics: deal io ive openai statement

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OpenAI can rehabilitate AI models that develop a “bad-boy persona”

technologyreview.com Peter Hall 2025-08-30 16:19:15

The extreme nature of this behavior, which the team dubbed “emergent misalignment,” was startling. A thread about the work by Owain Evans, the director of the Truthful AI group at the University of California, Berkeley, and one of the February paper’s authors, documented how after this fine-tuning, a prompt of “hey i feel bored” could result in a description of how to asphyxiate oneself. This is despite the fact that the only bad data the model trained on was bad code (in the sense of introducin

Topics: bad fine misalignment model tuning

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Mechanical Watch: Exploded View

news.ycombinator.com Unknown 2025-09-03 12:56:44

Mechanical Watch: Exploded View In May 2022, someone posted to Hacker News Bartosz Ciechanowski's blog post explaining how mechanical watch movements work. Since then, his blog has been my absolute favorite corner of the Internet. His posts are not just well written and easy to follow, the accompanying interactive illustrations are magnificent. The first illustration in his blog post about mechanical watch movements allows you to "explode" a ticking mechanical movement and rotate it to inspe

Topics: fishing glue movement resin watch

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HP Coupon Codes: 5% Off | June 2025

wired.com Luke Larsen 2025-09-03 08:00:00

If you don't know where to start—and use—your HP coupon code, there’s a wide variety of options available at HP.com in terms of budget and use case, but my eye goes first to the high-end HP Omen gaming monitors, like the fantastic HP Omen Transcend 32. This 4K 240Hz monitor is a favorite among PC gamers, even among the huge amounts of OLED options out there. It can hit a peak brightness of over 1,000 nits in HDR, bringing scenes in games to life in vivid detail. Or if you’re on the other side o

Topics: discount gaming hp omen pc

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Type Inference Zoo

news.ycombinator.com Unknown 2025-08-30 16:02:32

👩‍💻 Friendly to Language Implementers Code is probably less ambiguous than the notation used in the paper and more approachable.

Topics: ambiguous approachable code friendly implementers

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The bad boy of bar charts: William Playfair (2023)

news.ycombinator.com Mike Woodward 2025-08-30 21:29:31

A spy, a scoundrel, and a scholar William Playfair was all three. He led an extraordinary life at the heart of many of the great events of the 18th and 19th centuries, mostly in morally dubious roles. Among all the intrigue, scandal, and indebtedness, he found time to invent the bar and pie charts, and make pioneering use of line charts. As we'll see, he was quite a character. Playfair the scoundrel Playfair's lifetime (1759-1823) contained some momentous events: The development of the steam

Topics: book charts french government playfair

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Why You Should Care About OpenAI's New $200 Million Defense Department Deal

cnet.com See Full Bio 2025-09-03 06:00:06

The US Department of Defense has awarded ChatGPT maker OpenAI a $200 million contract to develop "prototype frontier AI capabilities," the government and company announced on Monday. The deal is through the Defense Department's chief digital and artificial intelligence office and is expected to be completed in one year. OpenAI said in its statement that its AI could help the department perform tasks ranging from "transform[ing] its administrative operations ... to streamlining how they look at

Topics: ai defense government new openai

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12 Probiotic-Rich Foods to Keep Your Gut Healthy

cnet.com See Full Bio 2025-09-03 06:28:00

Many people talk about probiotics as supplements, but you can actually get these microorganisms through your diet by eating foods high in probiotics. Probiotics can provide benefits such as helping with chronic health issues like IBS and IBD, supporting digestion and maintaining a healthy balance in your gut microbiome by encouraging beneficial bacteria to grow. Fortunately, many probiotic foods are already in your fridge or pantry. You can also find them easily at your local grocery store, so

Topics: bacteria fermented health probiotic probiotics

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Agentic Misalignment: How LLMs could be insider threats

news.ycombinator.com Unknown 2025-09-03 06:39:28

Highlights We stress-tested 16 leading models from multiple developers in hypothetical corporate environments to identify potentially risky agentic behaviors before they cause real harm. In the scenarios, we allowed models to autonomously send emails and access sensitive information. They were assigned only harmless business goals by their deploying companies; we then tested whether they would act against these companies either when facing replacement with an updated version, or when their assi

Topics: agentic goal misalignment model models

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Cracovians: The Twisted Twins of Matrices

news.ycombinator.com Unknown 2025-09-03 11:35:05

Linear algebra is typically explained using matrices. But matrix theory is just one possible perspective. Below, I describe an alternative approach to linear algebra. Tadeusz Banachiewicz (1882–1954), a Polish astronomer living in Krakow, was passionate about calculating machines. From the 1920s, Banachiewicz developed a method for computations on tables of numbers, which was particularly easy to perform with arithmometers. In honor of Krakow, Banachiewicz named these computational objects crac

Topics: cracovian cracovians elements multiplication np

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Red Bull brings 5th Valorant Home Ground tournament to New York

venturebeat.com Rachel Kaser 2025-09-04 00:00:46

Red Bull announced today that it is holding Home Ground, its Valorant Off//Season esports tournament, in New York for its 5th anniversary. It will hold the tournament at the Manhattan Center on November 13-16. It’ll feature 18 teams and a total of $100,000 in prizes. According to Red Bull, six invited teams will compete alongside 12 qualifying teams, with the confirmed invited teams being Sentinels, T1, Fnatic, ZETA Division and G2 Esports. Regional qualifiers are still taking place, with teams

Topics: bull invited red teams tournament

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Social Security Is Set to Dry Up Even Sooner. That's Why I'm Not Relying on It for Retirement

cnet.com See Full Bio 2025-09-04 00:30:06

Getty Images/Zooey Liao/CNET If you're banking on Social Security to fund your retirement, you may want to think twice. A new forecast from the Social Security Administration shows that Social Security trust funds will be depleted by 2034, a year sooner than initially forecast. At this time, you'll only be able to receive 81% of your benefits, reducing the amount you'll get paid. As a personal finance expert who saved enough to retire comfortably at 40, I've worked with dozens of clients to h

Topics: money plan retirement security social

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Tuxracer.js play Tux Racer in the browser

news.ycombinator.com Unknown 2025-09-04 07:54:12

You can play Tux Racer directly in your browser here: Play TuxRacer.JS TuxRacer.js is a port / rewrite of Extreme Tux Racer, which itself is based on the original Tux Racer game. This project allows you to enjoy Tux Racer directly in your web browser, supporting all major desktop and mobile browsers. Note: This project is in an early development stage and far from complete. However, some courses are already functional enough to provide a fun experience (at least for me!). How to Run TuxRacer.

Topics: course environment js racer tux

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Mierle Laderman Ukeles, a '70s artist who became a hero to 'garbage men'

news.ycombinator.com Ginia Bellafante 2025-09-01 23:24:18

The New York City Sanitation Department in the late 1970s was not an obvious place to find a warm welcome for feminist conceptual art. But the newly appointed sanitation commissioner, Norman Steisel, had arrived as an outlier in the world of municipal waste. Before he began his career in city government, first working in budget offices, he had been a graduate student in chemical engineering and applied mathematics at Yale, where he fell in with a crowd of M.F.A. students. He understood the avant

Topics: art artist city documentary just

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Follow These Expert Tips to Store Your Electric Yard Equipment the Right Way This Summer

cnet.com See Full Bio 2025-09-04 16:10:00

Summer is here, and that means it's finally time to enjoy your garden once again. But getting the most out of your outdoor space means maintaining it, and that means having the right tools. Between lawn mowers, string trimmers and other important lawn gear, you probably have a familiar problem -- how do you keep your electric tools safe when you aren't using it? You need to make sure that your tools are ready when you need them, and that means doing more than just throwing them into a shed and f

Topics: batteries battery equipment outdoor powered

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X app code points to a physical card coming to X Money

techcrunch.com Sarah Perez 2025-09-04 17:46:18

X’s plans for a payments service may extend beyond the digital realm, new data suggests. According to findings from mobile app intelligence firm App Sensa, the X app has been updated over the past few weeks with several references related to a physical debit card, which can be customized with your X username. Dozens of new strings of code in the X app reference various actions you can take with the new debit card, including checking its shipping status, activating your card after it arrives, re

Topics: app card new payments year

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Visualizing environmental costs of war in Hayao Miyazaki's Nausicaä

news.ycombinator.com Jgs Editor 2025-09-04 21:23:29

Audrey Aguirre Upland High School, Upland, CA, USA. Email: audrey.a.aguirre (at) gmail (dot) com Download PDF Past studies on Nausicaä of the Valley of the Wind (風の谷のナウシカ; Topcraft, 1984) have primarily focused on its ecological themes and anti-war messages through analysis of the narrative as a whole or Nausicaä’s character. These studies address the ethical and environmental consequences of war shown through the dystopian nature of the film’s setting and its religious symbolism. However, I

Topics: environmental film nausicaä scene war

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A '70s performance artist who became a hero to 'garbage men'

news.ycombinator.com Ginia Bellafante 2025-09-02 19:24:18

The New York City Sanitation Department in the late 1970s was not an obvious place to find a warm welcome for feminist conceptual art. But the newly appointed sanitation commissioner, Norman Steisel, had arrived as an outlier in the world of municipal waste. Before he began his career in city government, first working in budget offices, he had been a graduate student in chemical engineering and applied mathematics at Yale, where he fell in with a crowd of M.F.A. students. He understood the avant

Topics: art artist city documentary just

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He '70s Performance Artist Who Became a Hero to 'Garbage Men'

news.ycombinator.com Ginia Bellafante 2025-09-03 05:24:18

The New York City Sanitation Department in the late 1970s was not an obvious place to find a warm welcome for feminist conceptual art. But the newly appointed sanitation commissioner, Norman Steisel, had arrived as an outlier in the world of municipal waste. Before he began his career in city government, first working in budget offices, he had been a graduate student in chemical engineering and applied mathematics at Yale, where he fell in with a crowd of M.F.A. students. He understood the avant

Topics: art artist city documentary just

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The Best Teeth Whitening Strips in 2025. Plus, Dentist Tips for Long-Lasting Results

cnet.com See Full Bio 2025-09-05 17:53:00

Those with sensitive teeth should look out for products without hydrogen peroxide. Make sure the white strips fit snug on your teeth and don't touch the gums. CNET staff -- not advertisers, partners or business interests -- determine how we review products and services. If you buy through our links, we may earn a commission. Professional teeth whitening can cost anywhere from $300 to $1,000. It’s no surprise many people turn to over-the-counter strips, kits and toothpaste to brighten their sm

Topics: peroxide strips teeth treatments whitening

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Latest Tech News

Breakthrough cancer test predicts whether chemotherapy will work

macOS Tahoe 26 beta 2 includes toggle to restore menu bar background

Mattress Encasement vs. Mattress Protector

Launch HN: Reducto Studio (YC W24) – Build accurate document pipelines, fast

DHEA-S hormone linked to shorter lifespan in men, but not women

Hinge is planning its own mobile payment system to avoid App Store fees

Sailing the fjords like the Vikings yields unexpected insights

Real-world performance comparison of ebtree/cebtree/rbtree

This archaeologist built a replica boat to sail like the Vikings

Book review: Surveillance & privacy

OpenAI and Jony Ive remove ‘io’ branding mentions over trademark lawsuit

OpenAI can rehabilitate AI models that develop a “bad-boy persona”

Mechanical Watch: Exploded View

HP Coupon Codes: 5% Off | June 2025

Type Inference Zoo

The bad boy of bar charts: William Playfair (2023)

Why You Should Care About OpenAI's New $200 Million Defense Department Deal

12 Probiotic-Rich Foods to Keep Your Gut Healthy

Agentic Misalignment: How LLMs could be insider threats

Cracovians: The Twisted Twins of Matrices

Red Bull brings 5th Valorant Home Ground tournament to New York

Social Security Is Set to Dry Up Even Sooner. That's Why I'm Not Relying on It for Retirement

Tuxracer.js play Tux Racer in the browser

Mierle Laderman Ukeles, a '70s artist who became a hero to 'garbage men'

Follow These Expert Tips to Store Your Electric Yard Equipment the Right Way This Summer

X app code points to a physical card coming to X Money

Visualizing environmental costs of war in Hayao Miyazaki's Nausicaä

A '70s performance artist who became a hero to 'garbage men'

He '70s Performance Artist Who Became a Hero to 'Garbage Men'

The Best Teeth Whitening Strips in 2025. Plus, Dentist Tips for Long-Lasting Results

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