Scientists modeled how Mars' gravity field shifts over time due to solar tides, using a technique that lets gravity harmonic coefficients vary periodically at annual, semi-annual and other frequencies within orbit-determination software. By tracking these small periodic gravity variations, they detected a thermal anomaly located beneath the boundary separating Mars' northern lowlands and southern highlands, known as the crustal dichotomy.
Scientists grew high-purity single-crystal CrSb using chemical vapour transport and confirmed its structure through X-ray diffraction, resistivity, magnetization and Laue measurements. Using these bulk-resolved samples, they identified a three-dimensional g-wave altermagnetic order parameter in the material, characterizing how its magnetic symmetry differs from conventional magnets.
Researchers describe a newly analyzed stem-group insect fossil that shows features intermediate between aquatic arthropod ancestors and fully terrestrial hexapods, suggesting an amphibious lifestyle. The find, discussed alongside a broad review of arthropod and plant terrestrialization timelines, helps fill a gap in understanding how early insects transitioned from water to land.
Researchers introduced CIGMA, a statistical method that uses a linear mixed model to separate genetic effects on gene expression into components shared across cell types and components specific to individual cell types, applied to single-cell RNA sequencing data. The model uses cell-type-level pseudobulk expression averaged from single-cell data, requiring more than 10 cells per individual per cell type, and explicitly accounts for cell-to-cell noise within each individual and cell type.
Malva is a search system that lets scientists query massive single-cell and spatial transcriptomic datasets using gene names, DNA sequences, or plain-language descriptions like 'cells expressing markers of neurodegeneration.' It combines a language model, a k-mer-based search index, and a metadata service to return annotated cell results in formats compatible with common analysis tools such as scanpy.
This bibliography compiles foundational studies establishing systems vaccinology, a field using genomics and machine learning to predict and understand vaccine-induced immunity in humans. Key cited works include the 2009 study by Querec and colleagues, which first showed that blood transcriptional signatures could predict antibody responses to the yellow fever vaccine, and related papers on multilineage immune activation and pandemic vaccine response variability.
Researchers sequenced high-quality genomes from several Myotis bat species, including M. lucifugus and M. velifer, using field-collected tissue and cell lines to capture full sex-chromosome data. They combined this genomic data with lab experiments on PKR antiviral proteins in engineered human cells to study how bats' immune genes evolved under viral pressure.
Researchers describe a workflow that synthesizes and in-vitro-tests large pools of tRNA variants, including E. coli, M. alvus and M. mazei isoacceptors, using microchip-derived DNA oligo pools, T7-driven transcription, and cell-free translation systems. The method allows rapid amplification, refolding, purification and aminoacylation testing of tRNAs to evaluate their function outside living cells.
Scientists are exploring methods to repurpose radioactive waste material as fuel for radioisotope power systems used in deep-space missions. The approach would recycle byproducts from nuclear reactors instead of relying solely on scarce isotopes like plutonium-238 that are currently used to power spacecraft.
Scientists report that ocean surface temperatures have reached their highest levels ever measured, coinciding with an intensifying El Niño weather pattern. The warming trend spans large portions of the world's oceans and is being tracked closely by climate researchers monitoring its effects on marine and atmospheric systems.
Luffu, the family care app from Fitbit co-founders James Park and Eric Friedman, has introduced a screenless wearable called the Luffu Link, now available for US preorder for users 13 and older. The band uses 4G LTE and GPS to let wearers voice-log medications, meals, symptoms and moods, check in with family, and share location without needing a phone nearby. AI processes personal metrics like sleep, heart rate and activity, then feeds everything into the shared family app, where users can also track pet care.
Apple shared a short Instagram reel showing how its recent Mac mini with M6 commercial was made, featuring animators Justin Rasch and Scott DaRos and art director Josh Mahan. The clip highlights sketches, props, sculptures and stop-motion techniques used to build the ad's practical effects.
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