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The Next Acetaminophen Tablet You Take Could Be Made From PET

Researchers at the University of Edinburgh have succeeded in transforming certain plastic waste into acetaminophen using the natural properties of the common bacterium Escherichia coli (E. coli). This breakthrough represents a milestone with the potential to drive more sustainable methods of drug production and, at the same time, contribute to the reduction of plastic pollution globally. The study, led by Stephen Wallace, revealed that E. coli cells contain phosphate, an organic compound capabl

Spike in Pancreas Problems From Weight-Loss Drugs Prompts Investigation

Ozempic and similar GLP-1 drugs seem to be hurting some people’s pancreas. UK health officials are planning to study the link between GLP-1 use and acute pancreatitis, following an increase in reported cases this year. The Guardian reported Tuesday that the UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) is launching an investigation into pancreatitis associated with the drug class. Hundreds of residents have complained about pancreas problems after taking semaglutide or other r

Novo Nordisk Abruptly Ends Partnership with Hims, Claiming ‘Sham Compounding’ GLP-1 Drugs

Bad blood is brewing among some major players in the weight loss world. Novo Nordisk, the creator of Ozempic and Wegovy, cut short its partnership with telehealth company Hims & Hers Health Inc. over allegations that the latter is still trying to mass-market cheaper versions of the GLP-1 drugs. Bloomberg News reported the abrupt dissolution of the partnership Monday, just two months after it was struck. Novo claims that Hims is using “deceptive marketing” to widely sell compounded semaglutide t

Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s

Eli Lilly’s daily anti-obesity pill orforglipron appears to be as good at spurring weight loss and lowering blood sugar in diabetes patients as popular injectable GLP-1 drugs like Ozempic, according to new data from a Phase 3 trial. The results were announced today at the annual meeting of the American Diabetes Association and published in the New England Journal of Medicine. Eli Lilly is the maker of the blockbuster GLP-1 drug tirzepatide, approved as Mounjaro for type 2 diabetes and Zepbound

The FDA Just Approved a Long-Lasting Injection to Prevent HIV

The US Food and Drug Administration has just approved lenacapavir, an injectable form of HIV prevention that is almost 100 percent effective and requires only two doses per year. Science magazine described the medicine the most important scientific advance of 2024. In clinical trials, lenacapavir proved to be 99.9 percent effective in preventing HIV infection through sexual transmission in people weighing more than 35 kilograms. The drug, an antiretroviral, works not by stimulating an immune re

FDA Approves ‘Breakthough’ Drug to Prevent HIV

The Food and Drug Administration has just approved a preventative HIV drug widely regarded as a breakthrough. On Wednesday afternoon, the FDA approved Gilead Sciences’ lenacapavir as a more convenient form of pre-exposure prophylaxis (PrEP). In clinical trials, the drug was shown to be highly effective at preventing HIV infection when taken just twice a year. At the same time, advocates are urging Gilead and U.S. officials to ensure the drug is widely accessible to the public. “PrEP is one of

Surgery Still Beats Ozempic and Other GLP-1 Drugs in Real-World Weight Loss Study

When it comes to weight loss, surgery still reigns supreme. Research out today shows that people undergoing bariatric surgery tend to lose significantly more weight than people taking the newest, most effective GLP-1 medications for obesity. Scientists at New York University conducted the study, which analyzed real-world data from obesity patients. People who received surgery lost five times more weight over a two year span on average than those who were prescribed a GLP-1 drug, they found. The

Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

The Food and Drug Administration’s 2022 inspection of the Sun Pharma factory in India warned of contaminations and deficiencies. But the plant received permission from the FDA to continue shipping more than a dozen generic medications to Americans. We are still reporting. If you are a current or former FDA employee or someone in the industry with information about the agency, the safety of generic drugs, or the manufacturers that make them, our team wants to hear from you. Megan Rose can be rea

A New Obesity Pill May Burn Fat Without Suppressing Appetite

An experimental obesity pill that works in a different way from the wildly popular Ozempic may help people lose weight, according to results from a small, preliminary human trial. Ozempic and other GLP-1 drugs reduce food intake by stimulating a feeling of fullness. They act on the brain to promote satiety and on the gut to slow the movement of food through the stomach, helping people feel full longer. As a result, people on the drugs lose weight because they eat less. But a new drug may be ab

The Download: gambling with humanity’s future, and the FDA under Trump

—Bryan Gardiner This story is from the next print edition of MIT Technology Review, which explores power—who has it, and who wants it. It’s set to go live on Wednesday June 25, so subscribe & save 25% to read it and get a copy of the issue when it lands! Here’s what food and drug regulation might look like under the Trump administration Earlier this week, two new leaders of the US Food and Drug Administration published a list of priorities for the agency. Both Marty Makary and Vinay Prasad

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Here’s what food and drug regulation might look like under the Trump administration

First, a bit of background. Makary, the current FDA commissioner, is a surgeon and was a professor of health policy at the Johns Hopkins School of Public Health. He initially voiced support for stay-at-home orders during the pandemic but later changed his mind. In February 2021, he incorrectly predicted that the US would “have herd immunity by April.” He has also been very critical of the FDA, writing in 2021 that its then leadership acted like “a crusty librarian” and that drug approvals were “

The FDA Is Already Outsourcing Drug and Food Analysis to Error-Plagued AI Chatbot

Image by Getty / Futurism In case you haven't had enough about artificial intelligence, the US Food and Drug Administration is now outsourcing its oversight duties to a large language model (LLM.) In an article published in the Journal of the American Medical Association (JAMA), FDA bureaucrats Marty Makary and Vinay Prasad — the latter of whom is a noted critic of COVID mask mandates and vaccine boosters — laid out a five-point list of priorities that the federal agency is hoping to tackle. A

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Doctors Concerned By Massive Uptick In Teens Taking Ozempic

Image by Roberto Pfeil / picture alliance via Getty / Futurism Rx/Medicines Teens are being prescribed Ozempic and similar drugs more than ever before — and some doctors are worried about what the trend could mean. In interviews with Reuters and Raleigh, North Carolina's WRAL, doctors expressed disquiet at recent studies that found that are kids being prescribed the uber-popular jabs at increasing rates. Two recent studies, the first from the from the data firm Truveta and the second from Eve

Shares of Hims & Hers tumble 26% after FDA says semaglutide is no longer in shortage

Shares of Hims & Hers Health closed down around 26% on Friday after the U.S. Food and Drug Administration announced that the shortage of semaglutide injection products has been resolved. Semaglutide is the active ingredient in Novo Nordisk's blockbuster weight loss drug Wegovy and diabetes treatment Ozempic. Those medications are part of a class of drugs called GLP-1s, and demand for the treatments has exploded in recent years. As a result, digital health companies such as Hims & Hers have been