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Virtual cells

news.ycombinator.com Unknown 2025-09-05 09:18:38

Virtual cells Digital twins of biological cells—often referred to as virtual cells or whole-cell models (WCMs)–aim to recreate every relevant molecular process of a living cell in silico. This interdisciplinary endeavor marries systems biology, computational modeling, high-performance computing, and, increasingly, AI. All models are wrong, but some are alive. Somewhere in a data center right now, a virtual bacterium is dividing for the millionth time. Somewhere else, an AI-enhanced model is l

Topics: cell cells genes models virtual

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You can now create custom GPTs with any OpenAI model, but there’s a catch

9to5mac.com Marcus Mendes 2025-09-09 02:39:15

If you’ve been experimenting with custom GPTs inside ChatGPT, here’s a welcome upgrade: OpenAI now lets users pick from all available models when building or running a custom GPT, not just GPT-4o. Here’s how it works (and what’s missing). What are custom GPTs again? If you have no idea what this is, you’re not alone. OpenAI launched custom GPTs in late 2023, but the feature hasn’t exactly taken off the way the company probably hoped. Here’s how OpenAI describes them: “…custom versions of Chat

Topics: custom gpt gpts model openai

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Study: Meta AI model can reproduce almost half of Harry Potter book

arstechnica.com Unknown 2025-09-09 02:00:14

In recent years, numerous plaintiffs—including publishers of books, newspapers, computer code, and photographs—have sued AI companies for training models using copyrighted material. A key question in all of these lawsuits has been how easily AI models produce verbatim excerpts from the plaintiffs’ copyrighted content. For example, in its December 2023 lawsuit against OpenAI, The New York Times Company produced dozens of examples where GPT-4 exactly reproduced significant passages from Times sto

Topics: ai books companies models openai

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Virtual Cells

news.ycombinator.com Unknown 2025-09-06 00:18:38

Virtual cells Digital twins of biological cells—often referred to as virtual cells or whole-cell models (WCMs)–aim to recreate every relevant molecular process of a living cell in silico. This interdisciplinary endeavor marries systems biology, computational modeling, high-performance computing, and, increasingly, AI. All models are wrong, but some are alive. Somewhere in a data center right now, a virtual bacterium is dividing for the millionth time. Somewhere else, an AI-enhanced model is l

Topics: cell cells genes models virtual

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Tech giants unleash AI on weather forecasts: are they any good?

feeds.bbci.co.uk Unknown 2025-09-09 05:02:58

A wave of machine-learning weather models have been unleashed by some of the very biggest businesses on the planet. These challenge the orthodoxy of traditional physics-based computer forecasts that have been incrementally developed and improved over many decades. But are the machine learning models any good? The weather is a national obsession for us Brits, and it is no wonder given the huge changes that are seen and felt from one day to the next.

Topics: based learning machine models weather

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The Download: future grids, and bad boy bots

technologyreview.com Rhiannon Williams 2025-09-08 23:15:33

Is this the electric grid of the future? Lincoln Electric System, a publicly owned utility in Nebraska, is used to weathering severe blizzards. But what will happen soon—not only at Lincoln Electric but for all electric utilities—is a challenge of a different order. Utilities must keep the lights on in the face of more extreme and more frequent storms and fires, growing risks of cyberattacks and physical disruptions, and a wildly uncertain policy and regulatory landscape. They must keep pric

Topics: ai electric grid model power

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Midjourney adds AI video generation

engadget.com Unknown 2025-09-09 21:25:57

AI company Midjourney has released its first video model. This initial take on AI-generated video will allow users to animate their images, either ones made in Midjourney or uploaded from a different source. The initial results will be five-second clips that a user can opt to extend by four seconds up to four times. Videos can be generated on web only for now and require at least a $10 a month subscription to access. Introducing our V1 Video Model. It's fun, easy, and beautiful. Available at 10

Topics: ai generated midjourney model video

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Public/protected/private is an unnecessary feature

news.ycombinator.com Unknown 2025-09-08 05:56:04

public/protected/private is an unnecessary feature Regular code using this interface works great: Users can write generic code that works for any Vehicle, and use a Car with that code. The implementer of Car can restrict users to only ever use Car instances through the Vehicle interface, by only allowing construction of Car instances through, for example, a function make_car with return type Vehicle. But the interface doesn't work with inheritance: Users cannot write a generic class that can i

Topics: access car interface modifiers subclasses

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AMD Radeon RX 9060 XT PCIe Benchmark: 8GB vs. 16GB

techspot.com Steven Walton 2025-09-10 03:26:00

On store shelves, AMD's Radeon RX 9060 XT looks like a compelling option for gamers. It's affordable, backed by a trusted brand, and appears well-equipped for modern gaming. But there's a catch: the 8GB version is severely constrained by its limited video memory – a technical bottleneck that may not show up in standard benchmarks. That missing memory turns the 8GB model into a ticking time bomb for gamers hoping to future-proof their rigs. The 8GB RX 9060 XT is marketed under the same name as t

Topics: 16gb 8gb model pcie performance

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Inside Microsoft’s complicated relationship with OpenAI

theverge.com Tom Warren 2025-09-10 09:00:00

is a senior editor and author of Notepad , who has been covering all things Microsoft, PC, and tech for over 20 years. Beyond the selfies between Microsoft CEO Satya Nadella and OpenAI CEO Sam Altman, and the friendly conversations between the pair on stage, all is not well with Microsoft’s $13 billion AI investment. Over the past year, multiple reports have painted a picture of a Microsoft and OpenAI relationship that is straining under pressure. As OpenAI battles for access to more compute p

Topics: ai microsoft models openai year

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OpenAI’s Sam Altman discusses GPT-5 release date

bleepingcomputer.com Unknown 2025-09-10 13:43:06

ChatGPT's next big upgrade, or the new foundational model 'GPT-5,' is being prepared for public release, but OpenAI won't share the specifics. In a recent interview, Sam Altman, CEO and co-founder of OpenAI, confirmed that ChatGPT's GPT-5 model release date is sometime in summer, but it depends on a number of factors. OpenAI has internal benchmarks and other standards set for GPT-5, and unless those are met, OpenAI might not release the model to the public. Sam added that he doesn't know 'exa

Topics: better big gpt model openai

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Steam is adding screen reader support and other accessibility tools

theverge.com Adi Robertson 2025-09-10 21:00:15

is a senior tech and policy editor focused on VR, online platforms, and free expression. Adi has covered video games, biohacking, and more for The Verge since 2011. Valve is introducing accessibility features for players with disabilities in its latest beta for Steam Big Picture Mode and SteamOS. The features — listed in full and explained here — include options to modify the Steam UI, like a high contrast mode, as well as a built-in screen reader for SteamOS. In its post, Valve describes the

Topics: features mode screen steam steamos

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AMD Radeon RX 9060 XT PCIe Comparison: 8GB vs. 16GB

techspot.com Steven Walton 2025-09-11 09:26:00

On store shelves, AMD's Radeon RX 9060 XT looks like a compelling option for gamers. It's affordable, backed by a trusted brand, and appears well-equipped for modern gaming. But there's a catch: the 8GB version is severely constrained by its limited video memory – a technical bottleneck that may not show up in standard benchmarks. That missing memory turns the 8GB model into a ticking time bomb for gamers hoping to future-proof their rigs. The 8GB RX 9060 XT is marketed under the same name as t

Topics: 16gb 8gb model pcie performance

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AMD Radeon RX 9060 XT PCIe Comparison: 8GB vs. 16GB

techspot.com Steven Walton 2025-09-11 09:26:00

On store shelves, AMD's Radeon RX 9060 XT looks like a compelling option for gamers. It's affordable, backed by a trusted brand, and appears well-equipped for modern gaming. But there's a catch: the 8GB version is severely constrained by its limited video memory – a technical bottleneck that may not show up in standard benchmarks. That missing memory turns the 8GB model into a ticking time bomb for gamers hoping to future-proof their rigs. The 8GB RX 9060 XT is marketed under the same name as t

Topics: 16gb 8gb model pcie performance

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Why Some AI Models Spew 50 Times More Greenhouse Gas to Answer the Same Question

gizmodo.com Natalia Mesa 2025-09-11 08:00:55

Like it or not, large language models have quickly become embedded into our lives. And due to their intense energy and water needs, they might also be causing us to spiral even faster into climate chaos. Some LLMs, though, might be releasing more planet-warming pollution than others, a new study finds. Queries made to some models generate up to 50 times more carbon emissions than others, according to a new study published in Frontiers in Communication. Unfortunately, and perhaps unsurprisingly,

Topics: emissions energy models reasoning study

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The best iPad deals you can get right now

theverge.com Brandon Widder 2025-09-11 10:47:17

While the best iPad deals usually land during major sale events like Black Friday and Prime Day, many great iPad deals are attainable outside of those times. The day-to-day discounts may come and go like changing winds, but there’s often some amount to be saved, particularly on Apple’s most affordable iPad. The most recent iPad Pro and iPad Mini are also regularly discounted, as is the latest iPad Air. It’s difficult to know where exactly you can find the most notable iPad deals unless you’re s

Topics: amazon deals ipad model starting

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I'm Talking Back to Google's New Search Live Mode for AI Convos About Big Events

cnet.com See Full Bio 2025-09-12 05:02:00

Google's latest AI addition makes Google searches conversational on your phone with Search Live -- and I love being able to interrupt it. While Google's AI Mode search has been available to Google Labs participants for some time, the company rolled out the Search Live function on June 18 for iOS and Android users. You can access it through a new AI Mode icon -- a star above three audio lines. This creates an ongoing conversation with Google's search engine that's significantly different than wh

Topics: ai google live mode search

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Midjourney launches its first AI video generation model, V1

techcrunch.com Maxwell Zeff 2025-09-12 05:21:21

Midjourney, one of the most popular AI image generation startups, announced on Wednesday the launch of its much-anticipated AI video generation model, V1. V1 is an image-to-video model, in which users can upload an image — or take an image generated by one of Midjourney’s other models — and V1 will produce a set of four five-second videos based on it. Much like Midjourney’s image models, V1 is only available through Discord, and it’s only available on the web at launch. Introducing our V1 Vide

Topics: ai midjourney models v1 video

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OpenAI can rehabilitate AI models that develop a “bad boy persona”

technologyreview.com Peter Hall 2025-09-12 09:19:15

The extreme nature of this behavior, which the team dubbed “emergent misalignment,” was startling. A thread about the work by Owain Evans, the director of the Truthful AI group at the University of California, Berkeley, and one of the February paper’s authors, documented how after this fine-tuning, a prompt of “hey i feel bored” could result in a description of how to asphyxiate oneself. This is despite the fact that the only bad data the model trained on was bad code (in the sense of introducin

Topics: bad fine misalignment model tuning

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Wyze adds major security update to its security cameras after numerous security lapses

engadget.com Unknown 2025-09-12 09:17:35

Wyze, the Seattle-based tech company that specializes in smart home products and wireless cameras, has released a major security update that it hopes will rebuild some lost trust. The company has been plagued by numerous security failures over the past few years, most notably when an AWS outage led to thousands of users gaining access to recorded videos from other people’s homes. That incident, paired with the company’s history of lackluster responses to security flaws, even led The New York Tim

Topics: company models security update wyze

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Revisiting Minsky's Society of Mind in 2025

news.ycombinator.com Sutha Kamal 2025-09-12 11:40:12

A Teenager’s Frustration, a Researcher’s Revelation (Note: this is a deeply nerdy / technical post, with most applicability to folks building AI systems, and of little relevance to most users of AI.) In the late 90s, as a tech-obsessed teenager, I picked up Marvin Minsky’s 1986 book The Society of Mind expecting profound answers about intelligence. It was exciting: Minsky made AI seem so tractable, with beautiful essays arguing that the mind is composed of countless simple “agents” – little pr

Topics: agent ai minsky model society

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Game Hacking – Valve Anti-Cheat (VAC)

news.ycombinator.com Unknown 2025-09-12 13:19:31

Intro In 2002 Valve created an Anti-Cheat solution called “Valve Anti-Cheat” aka VAC. The first game they implemented VAC into was Counter-Strike. When VAC was introduced it only operated in User Mode (Still does) meaning it runs entirely in user space and has no kernel component. Below is a list of games that use VAC.. Call of Duty: Modern Warfare 2 Call of Duty: Modern Warfare 3 Counter-Strike (video game) Counter-Strike: Condition Zero Counter-Strike: Source Counter-Strike 2 Day of Defeat

Topics: dll function modules steamservice vac

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OpenAI found features in AI models that correspond to different ‘personas’

techcrunch.com Maxwell Zeff 2025-09-12 13:10:58

OpenAI researchers say they’ve discovered hidden features inside AI models that correspond to misaligned “personas,” according to new research published by the company on Wednesday. By looking at an AI model’s internal representations — the numbers that dictate how an AI model responds, which often seem completely incoherent to humans — OpenAI researchers were able to find patterns that lit up when a model misbehaved. The researchers found one such feature that corresponded to toxic behavior i

Topics: ai model models openai research

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This AI Model Never Stops Learning

wired.com Will Knight 2025-09-12 17:00:00

Modern large language models (LLMs) might write beautiful sonnets and elegant code, but they lack even a rudimentary ability to learn from experience. Researchers at Massachusetts Institute of Technology (MIT) have now devised a way for LLMs to keep improving by tweaking their own parameters in response to useful new information. The work is a step toward building artificial intelligence models that learn continually—a long-standing goal of the field and something that will be crucial if machi

Topics: ai model models new seal

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Google tests real-time AI voice chats in Search

theverge.com Emma Roth 2025-09-12 17:00:00

is a news writer who covers the streaming wars, consumer tech, crypto, social media, and much more. Previously, she was a writer and editor at MUO. Google is building Search Live into AI Mode, allowing you to have a back-and-forth voice conversation with the company’s AI chatbot right from its search engine. The test, which is rolling out now to Labs users in the US, currently doesn’t support camera-sharing, but Google plans to add the capability in the “coming months.” Search Live lets you in

Topics: ai google live mode search

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Google’s AI Mode can now have back-and-forth voice conversations

techcrunch.com Aisha Malik 2025-09-12 17:00:00

Google is rolling out the ability for users to have a back-and-forth voice conversation with AI Mode, its experimental Search feature that lets users ask complex, multi-part questions. With the new Search Live integration, users can have a free-flowing voice conversation with Search and explore links from across the web. Users will be able to access the feature by opening the Google app and tapping the new “Live” icon to ask their question aloud. They will then hear an AI-generated audio respon

Topics: ai google live mode search

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Demystifying Multi-Modal AI

computer.org Laurel Tweed 2025-09-12 19:00:39

Artificial Intelligence has come a long way in understanding language, recognizing images, and interpreting sound—but what happens when it can do all of that at once? That’s where Multi-Modal AI steps in: a new frontier where machines learn to process and combine information from different types of input—like text, images, audio, and video—just as humans do. What Is Multi-Modal AI? Multi-modal AI refers to systems that can understand and reason across multiple forms of data. For example, a sin

Topics: ai data like modal multi

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The first Snapdragon G3 Gen 3 handheld is here, complete with a shocking 10,000mAh battery

androidauthority.com Unknown 2025-09-13 01:21:56

AYANEO TL;DR The AYANEO Pocket S2 is the first device with a Snapdragon G3 Gen 3 chipset. The standard model has a 8,000mAh battery, with the Pro model upping that to 10,000mAh. It’s available for pre-order now, with shipping expected to start at the end of July. AYANEO is the most boutique brand when it comes to Android gaming handhelds, and its latest release doesn’t pull any punches. The AYANEO Pocket S2 is now available on Indiegogo, and it sports the latest chipset, an upgraded design,

Topics: ayaneo model pocket pro s2

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Scientists once hoarded pre-nuclear steel; now we’re hoarding pre-AI content

arstechnica.com Unknown 2025-09-13 08:15:46

Former Cloudflare executive John Graham-Cumming recently announced that he launched a website, lowbackgroundsteel.ai, that treats pre-AI, human-created content like a precious commodity—a time capsule of organic creative expression from a time before machines joined the conversation. "The idea is to point to sources of text, images and video that were created prior to the explosion of AI-generated content," Graham-Cumming wrote on his blog last week. The reason? To preserve what made non-AI medi

Topics: ai created data generated models

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I counted all of the yurts in Mongolia using machine learning

news.ycombinator.com Unknown 2025-09-13 14:58:18

The Fall of Civilizations podcast put out a 6¾-hour episode on the history of the Mongol Empire, which I eagerly listened to. After finishing the episode I wondered about contemporary Mongolian society, I wanted to learn what the lands that the Mongol Empire exploded from are like in our current day. There are many ways to try to understand a society, whether it be quantifying it or looking at the lived experiences within it. If you look at data provided by the World Bank, you’ll see a country t

Topics: data model tile tiles yurts

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Latest Tech News

Virtual cells

You can now create custom GPTs with any OpenAI model, but there’s a catch

Study: Meta AI model can reproduce almost half of Harry Potter book

Virtual Cells

Tech giants unleash AI on weather forecasts: are they any good?

The Download: future grids, and bad boy bots

Midjourney adds AI video generation

Public/protected/private is an unnecessary feature

AMD Radeon RX 9060 XT PCIe Benchmark: 8GB vs. 16GB

Inside Microsoft’s complicated relationship with OpenAI

OpenAI’s Sam Altman discusses GPT-5 release date

Steam is adding screen reader support and other accessibility tools

AMD Radeon RX 9060 XT PCIe Comparison: 8GB vs. 16GB

AMD Radeon RX 9060 XT PCIe Comparison: 8GB vs. 16GB

Why Some AI Models Spew 50 Times More Greenhouse Gas to Answer the Same Question

The best iPad deals you can get right now

I'm Talking Back to Google's New Search Live Mode for AI Convos About Big Events

Midjourney launches its first AI video generation model, V1

OpenAI can rehabilitate AI models that develop a “bad boy persona”

Wyze adds major security update to its security cameras after numerous security lapses

Revisiting Minsky's Society of Mind in 2025

Game Hacking – Valve Anti-Cheat (VAC)

OpenAI found features in AI models that correspond to different ‘personas’

This AI Model Never Stops Learning

Google tests real-time AI voice chats in Search

Google’s AI Mode can now have back-and-forth voice conversations

Demystifying Multi-Modal AI

The first Snapdragon G3 Gen 3 handheld is here, complete with a shocking 10,000mAh battery

Scientists once hoarded pre-nuclear steel; now we’re hoarding pre-AI content

I counted all of the yurts in Mongolia using machine learning

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