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Virtual cells

Virtual cells Digital twins of biological cells—often referred to as virtual cells or whole-cell models (WCMs)–aim to recreate every relevant molecular process of a living cell in silico. This interdisciplinary endeavor marries systems biology, computational modeling, high-performance computing, and, increasingly, AI. All models are wrong, but some are alive. Somewhere in a data center right now, a virtual bacterium is dividing for the millionth time. Somewhere else, an AI-enhanced model is l

BBC threatens AI firm with legal action over unauthorised content use

BBC threatens AI firm with legal action over unauthorised content use 1 hour ago Share Save Liv McMahon Technology reporter Share Save Getty Images The BBC is threatening to take legal action against an artificial intelligence (AI) firm whose chatbot the corporation says is reproducing BBC content "verbatim" without its permission. The BBC has written to Perplexity, which is based in the US, demanding it immediately stops using BBC content, deletes any it holds, and proposes financial compens

How a 30-year-old techno-thriller predicted our digital isolation

How much will you trust an AI chatbot powered by Meta to be your friend? Answers to this may vary. Even if you won’t, other people are already making close connections with “AI companions” or “falling in love” with ChatGPT. The rise of “cognitive offloading”—of people asking AI to do their critical thinking for them—is already well underway, with many high school and college students admitting to a deep reliance on the technology. Beyond the obvious concern that AI “friends” are hallucinating,

You can now create custom GPTs with any OpenAI model, but there’s a catch

If you’ve been experimenting with custom GPTs inside ChatGPT, here’s a welcome upgrade: OpenAI now lets users pick from all available models when building or running a custom GPT, not just GPT-4o. Here’s how it works (and what’s missing). What are custom GPTs again? If you have no idea what this is, you’re not alone. OpenAI launched custom GPTs in late 2023, but the feature hasn’t exactly taken off the way the company probably hoped. Here’s how OpenAI describes them: “…custom versions of Chat

My search for the ultimate wireless charger is over. This one will satisfy the biggest Apple fans

'ZDNET Recommends': What exactly does it mean? ZDNET's recommendations are based on many hours of testing, research, and comparison shopping. We gather data from the best available sources, including vendor and retailer listings as well as other relevant and independent reviews sites. And we pore over customer reviews to find out what matters to real people who already own and use the products and services we’re assessing. When you click through from our site to a retailer and buy a product or

You can download the iOS 26 beta on your iPhone right now. Here's how (and which models support it)

'ZDNET Recommends': What exactly does it mean? ZDNET's recommendations are based on many hours of testing, research, and comparison shopping. We gather data from the best available sources, including vendor and retailer listings as well as other relevant and independent reviews sites. And we pore over customer reviews to find out what matters to real people who already own and use the products and services we’re assessing. When you click through from our site to a retailer and buy a product or

I've tested dozens of robot vacuums. These are the three I recommend most to family and friends

'ZDNET Recommends': What exactly does it mean? ZDNET's recommendations are based on many hours of testing, research, and comparison shopping. We gather data from the best available sources, including vendor and retailer listings as well as other relevant and independent reviews sites. And we pore over customer reviews to find out what matters to real people who already own and use the products and services we’re assessing. When you click through from our site to a retailer and buy a product or

Should you buy tools from Amazon Basics? Here's my verdict after testing a bunch for weeks

'ZDNET Recommends': What exactly does it mean? ZDNET's recommendations are based on many hours of testing, research, and comparison shopping. We gather data from the best available sources, including vendor and retailer listings as well as other relevant and independent reviews sites. And we pore over customer reviews to find out what matters to real people who already own and use the products and services we’re assessing. When you click through from our site to a retailer and buy a product or

He '70s Performance Artist Who Became a Hero to 'Garbage Men'

The New York City Sanitation Department in the late 1970s was not an obvious place to find a warm welcome for feminist conceptual art. But the newly appointed sanitation commissioner, Norman Steisel, had arrived as an outlier in the world of municipal waste. Before he began his career in city government, first working in budget offices, he had been a graduate student in chemical engineering and applied mathematics at Yale, where he fell in with a crowd of M.F.A. students. He understood the avant

Nintendo Switch 2 Review: The Ultimate Handheld and It’s Not Even Close

2025 After the massive flop that was the Wii U, consumers had every reason to believe the original Switch, released in 2017, would be yet another Nintendo gimmick that would push people to buy a PlayStation or Xbox instead. But the original $300 Switch’s handheld/console design, with its detachable Joy-Con controllers, proved to be a major hit with gamers of all ages. The handheld and TV-dockable game system was inventive and could be understood immediately. It felt like another Wii moment for

Schedule a Text to Send Later With This iPhone Trick

Apple announced at its Worldwide Developers Conference on June 9 that the next version of the iPhone's operating system will be called iOS 26, not iOS 19. The tech giant also announced that iOS 26 will bring a transparent glass design to your iPhone's icons, menus and more. But when Apple released iOS 18 in September 2024, that update brought a feature to Messages that lets you schedule messages to send later called, simply, Send Later. The feature does what its name implies and lets you schedu

The Best Teeth Whitening Strips in 2025. Plus, Dentist Tips for Long-Lasting Results

Those with sensitive teeth should look out for products without hydrogen peroxide. Make sure the white strips fit snug on your teeth and don't touch the gums. CNET staff -- not advertisers, partners or business interests -- determine how we review products and services. If you buy through our links, we may earn a commission. Professional teeth whitening can cost anywhere from $300 to $1,000. It’s no surprise many people turn to over-the-counter strips, kits and toothpaste to brighten their sm

Study: Meta AI model can reproduce almost half of Harry Potter book

In recent years, numerous plaintiffs—including publishers of books, newspapers, computer code, and photographs—have sued AI companies for training models using copyrighted material. A key question in all of these lawsuits has been how easily AI models produce verbatim excerpts from the plaintiffs’ copyrighted content. For example, in its December 2023 lawsuit against OpenAI, The New York Times Company produced dozens of examples where GPT-4 exactly reproduced significant passages from Times sto

How AI Is Helping Kids Find the Right College

After Julia Dixon graduated from the University of Michigan in 2014, her family and friends asked for her help with the college application process. Dixon was happy to share her recently earned expertise about the world of higher education but soon realized how many parents and students in her community needed help and how hard it was for them to access that support. The ratio of college counselors to students in the US, according to the American School Counselor Association, is one for every 3

The FDA Just Approved a Long-Lasting Injection to Prevent HIV

The US Food and Drug Administration has just approved lenacapavir, an injectable form of HIV prevention that is almost 100 percent effective and requires only two doses per year. Science magazine described the medicine the most important scientific advance of 2024. In clinical trials, lenacapavir proved to be 99.9 percent effective in preventing HIV infection through sexual transmission in people weighing more than 35 kilograms. The drug, an antiretroviral, works not by stimulating an immune re

I replaced my TV with a 4K UST projector - and the visual upgrade was massive

ZDNET's key takeaways The Formovie Cinema Edge 4K UST projector is available now for $1,899 at Amazon. It has a sturdy construction and sleek design. It's great for cinematic viewing, although it could greatly benefit from having a dedicated sound system. $1,899 at Amazon The first ultra short-throw (UST) projectors hit the mainstream market in the US as early as 2014. (Thank you, Sony.) Collectively, they've come a long way since then in terms of design, performance, and affordability. Yet,

Cannabis scientists are trying to find a predictable, reliable product (2020)

As more of the compounds in cannabis are isolated, a few companies are looking at ways to eliminate one stubborn source of variability: the plants themselves. Ebbu’s intellectual property includes a patent for using an inkjet printer to spit out cannabinoids and terpenes in precisely measured ratios determined by the user. Brought in from the black-market wilderness by deep-pocketed, consumer-savvy companies, cannabis may become just another designer drug. At INSA, the Jack Herer vape oil may b

Qfex (YC X25) – Founding Back End Engineer for a 24/7 Stock Exchange

Founding Backend Engineer Mission QFEX is building a team of founding engineers who can design, code and own systems that will soon process billions of dollars in trading volume every single day. This is an incredible opportunity to work alongside a very well-backed team of builders from some of the biggest financial companies in the world (Citadel, Kraken, Tower Research Capital) and change the course of financial history. What You’ll Do Reliability & performance Design fault-tolerant, low

Virtual Cells

Virtual cells Digital twins of biological cells—often referred to as virtual cells or whole-cell models (WCMs)–aim to recreate every relevant molecular process of a living cell in silico. This interdisciplinary endeavor marries systems biology, computational modeling, high-performance computing, and, increasingly, AI. All models are wrong, but some are alive. Somewhere in a data center right now, a virtual bacterium is dividing for the millionth time. Somewhere else, an AI-enhanced model is l

Here’s My Experience With 5 Cheap Gadgets I Bought From AliExpress

If you're shopping online, you may have noticed products from Temu and AliExpress often come up in your shopping search. These items are so cheap that you may wonder if it's really a steal or if you should stay away. I was in that boat as well. And I love a good YouTube video where the host tests cheap tech from low-cost retailers. So, curious as I am, I decided to try my hand at testing cheap home products from the popular discount marketplace, AliExpress. Now, when shopping for a new piece of

Octobass

Composers and orchestras like to use their lowest instruments sparingly, for maximum impact. Few instruments go lower and are used more sparingly than the huge and strange octobass, one of the rarest classic instruments in existence. Invented in 1850 by Jean-Baptiste Vuillaume, the octobass was intended to bring an extremely deep rumble to the orchestra sound. The three-stringed instrument stands between 11 and 12 feet tall, about twice the height of a double bass. This giant bass produces soun

No, the 16 billion credentials leak is not a new data breach

News broke today of a "mother of all breaches," sparking wide media coverage filled with warnings and fear-mongering. However, it appears to be a compilation of previously leaked credentials stolen by infostealers, exposed in data breaches, and via credential stuffing attacks. To be clear, this is not a new data breach, or a breach at all, and the websites involved were not recently compromised to steal these credentials. Instead, these stolen credentials were likely circulating for some time,

In praise of “normal” engineers

This article was originally commissioned by Luca Rossi (paywalled) for refactoring.fm, on February 11th, 2025. Luca edited a version of it that emphasized the importance of building “10x engineering teams” . It was later picked up by IEEE Spectrum (!!!), who scrapped most of the teams content and published a different, shorter piece on March 13th. This is my personal edit. It is not exactly identical to either of the versions that have been publicly released to date. It contains a lot of the so

Estrogen: A Trip Report

The following blog post discusses my personal experience of the phenomenology of feminising hormone therapy. It will also touch upon my own experience of gender dysphoria. I wish to be clear that I do not believe that someone should have to demonstrate that they experience gender dysphoria – however one might even define that – as a prerequisite for taking hormones. At smoothbrains.net, we hold as self-evident the right to put whatever one likes inside one’s body; and this of course includes hor

Trump gives TikTok another ban extension

is a senior policy reporter at The Verge, covering the intersection of Silicon Valley and Capitol Hill. She spent 5 years covering tech policy at CNBC, writing about antitrust, privacy, and content moderation reform. For the third time, President Donald Trump has extended the deadline for TikTok to spin out from its Chinese parent company or face a US ban. As White House Press Secretary Karoline Leavitt confirmed in a statement Tuesday, Trump signed an executive order on Thursday extending the

Midjourney adds AI video generation

AI company Midjourney has released its first video model. This initial take on AI-generated video will allow users to animate their images, either ones made in Midjourney or uploaded from a different source. The initial results will be five-second clips that a user can opt to extend by four seconds up to four times. Videos can be generated on web only for now and require at least a $10 a month subscription to access. Introducing our V1 Video Model. It's fun, easy, and beautiful. Available at 10