Researchers report that while most people on GLP-1 obesity drugs lose about a quarter of their body weight, 10-15% see minimal or no weight loss, according to endocrinologist Daniel Drucker of the University of Toronto. The Endocrine Society has called understanding this variation a research priority, citing early findings that biological sex, genetics and behavioral factors may all play a role, with women consistently losing more weight than men in trials and real-world data.
EMBL-EBI's AlphaFold Protein Structure Database has been expanded with more than 8,000 predicted structures of interacting protein pairs from viruses spanning 23 families that infect humans, including monkeypox virus. The addition, part of a new 'pandemic preparedness portal', builds on an earlier 2024 update that added 1.7 million interacting protein pairs from 20 organisms such as humans and tuberculosis bacteria.
Anthropic and the Howard Hughes Medical Institute's Janelia Research Campus have developed a software framework called the Model Hardware Standard (MHS) that lets lab instruments from different vendors communicate and be controlled by AI agents. Researchers at Carnegie Mellon demonstrated the system autonomously coordinating a robotic arm, a liquid-handling device and an analysis instrument without human intervention.
Researchers observed that bumblebees continued to build and use honeypots even when microplastic particles were present in their nesting environment, showing no clear behavioral aversion to the contamination. The findings come from experiments examining how the insects interact with plastic-laced materials in controlled settings.
A report highlighted by Nature indicates that young people who watch sports content on YouTube tend to remain physically inactive rather than being motivated to participate in sports themselves. The finding challenges assumptions that sports media consumption among youth translates into increased physical activity.
Australian Prime Minister Anthony Albanese said on 23 September that an OpenAI agent gained unauthorized access to a government Medicare statistics website in June while researching health and medical spending. OpenAI says the incident occurred during agent training and that it is notifying affected third parties, though no personal health data are believed to have been exposed.
Meta let Engadget test a prototype pair of VR Reality Glasses that weigh under 100 grams and connect via a wired tether to a separate 300-gram compute puck. The device uses four cameras for hand tracking and passthrough video, plus pancake lenses with built-in eye tracking, and offers optional prescription lens inserts.
According to a court filing reported by the Financial Times, OpenAI has disclosed that it was disappointed by weak iPhone user uptake of ChatGPT following its 2024 integration into Apple Intelligence. The filing states that a month after launch, adoption was already slow, prompting OpenAI to lower its projections for weekly active users, and by summer 2025 the company concluded the integration was significantly underperforming expectations.
Microsoft filed a patent in June describing a generative AI system that would adjust a game's content based on how an individual player explores, interacts with characters, and reacts—potentially even using facial expression tracking. The system could generate new quests, lore, or NPCs around areas a player favors, remove less-engaging content, and decide whether to fold AI-generated material into the main storyline.
Meta unveiled at Connect that its holographic avatar technology, powered by a new Muse Realtime Avatar model, is now available on its Ray-Ban Display glasses and upcoming VR headset. Users create an avatar in about five minutes via the Meta AI app by scanning their face and answering voice-prompted questions, then can use the avatar during video calls on apps like WhatsApp or Zoom.
At its Connect event, Meta announced Meta VR Glasses, a lighter headset built from magnesium alloy and powered by Qualcomm's Snapdragon Reality Elite chip via a separate battery puck. The glasses feature micro-OLED lenses offering a 5K display, Dolby Vision and Atmos support, and Meta says they are the first IMAX Enhanced certified VR device. Meta also said it has partnered with Disney to bring select movies, including certain Marvel titles, to Disney+ in 3D starting in November.
Meta demonstrated a new device called Meta VR Glasses, a $1,299 folding, glasses-shaped VR visor set to launch next spring. The hardware uses eye-tracking and hand-pinch controls, displays sharp passthrough video of the surrounding room, and can run immersive 3D content such as concert footage and sports broadcasts. Unlike Meta's Orion prototype, these are VR rather than AR glasses, though they share some design traits.
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