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Diabetic Man With Gene-Edited Cells Produces His Own Insulin—No Transplant Drugs Required

gizmodo.com Ed Cara 2025-12-05 16:20:36

A new case study offers a tantalizing glimpse into the potential future of transplantation medicine. A man with type 1 diabetes is now able to make his own insulin thanks to a transplant of gene-edited pancreatic cells—a transplant that hasn’t required the typical drugs used to avoid rejection. Scientists in Sweden and the U.S. conducted the research, published this week in the New England Journal of Medicine. The 42-year-old man with long-standing diabetes was given donated islet cells that we

Topics: cells donated immune insulin man

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Trump’s Golden Dome Sparks Unprecedented Surge in Space Force Funding

gizmodo.com Passant Rabie 2025-12-05 16:50:40

The U.S. Space Force’s budget for 2026 could see a 40% increase compared to this year, which is mostly driven by President Donald Trump’s fantasy of creating a futuristic missile defense system that uses space-based sensors and weapons. A recent report by the Center for Space Policy and Strategy highlights the Golden Dome’s role in driving the increase in funding allocated toward the Space Force. Trump announced the ambitious Golden Dome project within one week of taking office, describing a mu

Topics: budget defense dome golden space

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OpenStore’s demise marks endgame for once-booming e-commerce aggregator market

cnbc.com Annie Palmer 2025-12-05 21:40:47

When venture capitalist Keith Rabois got into e-commerce, he couldn't stop buying brands. Now, everything must go. OpenStore, co-founded by Rabois in 2021, is shutting down nearly all of the 40-plus Shopify stores it acquired, and it's in the process of liquidating any remaining inventory by offering steep discounts to move merchandise. Earlier this week, the company announced it plans to focus solely on growing Jack Archer, the menswear brand it bought for $837,000 in 2022. The website addres

Topics: brand commerce company openstore rabois

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Amtrak NextGen Acela Debuts on August 28

news.ycombinator.com Beth Toll 2025-12-05 20:30:23

A new era of high-speed rail to begin between Boston and Washington, DC WASHINGTON – All aboard the future of East Coast travel! Starting Thursday, Aug. 28, customers can travel on Amtrak’s NextGen Acela – America’s high-speed train – connecting the Northeast Corridor between Washington, D.C., New York City, and Boston. 🛤️ This historic launch introduces: More trains : 28 brand-new trains entering service through 2027 : 28 brand-new trains entering service through 2027 More seats : 27% more

Topics: acela amtrak new nextgen trains

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Royal and BlackSuit ransomware gangs hit over 450 US companies

bleepingcomputer.com Unknown 2025-12-06 03:36:34

The U.S. Department of Homeland Security (DHS) says the cybercrime gang behind the Royal and BlackSuit ransomware operations had breached hundreds of U.S. companies before being taken down last month. Homeland Security Investigations (HSI), DHS's main investigative arm, which took down the group's infrastructure in cooperation with international law enforcement partners, added that the cybercriminals also collected over $370 million from their victims. "Since 2022, the Royal and BlackSuit rans

Topics: blacksuit chaos gang ransomware royal

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Microsoft will kill the Lens PDF scanner app for iOS, Android

bleepingcomputer.com Unknown 2025-12-06 05:59:19

Microsoft announced that it will phase out the Microsoft Lens PDF scanner app for Android and iOS devices starting in September. Microsoft Lens (formerly known as Office Lens) can convert images into PDF, Word, PowerPoint, and Excel files, and it is capable of scanning both printed and handwritten text. Currently, the app has been downloaded 50 million times on the Google Play Store (with over 952,000 reviews with an average of 4.9/5 rating) and received nearly 136,000 ratings on Apple's App St

Topics: app lens microsoft scans users

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How Attention Sinks Keep Language Models Stable

news.ycombinator.com Guangxuan Xiao 2025-12-06 04:53:10

We discovered why language models catastrophically fail on long conversations: when old tokens are removed to save memory, models produce complete gibberish. We found models dump massive attention onto the first few tokens as "attention sinks"—places to park unused attention since softmax requires weights to sum to 1. Our solution, StreamingLLM, simply keeps these first 4 tokens permanently while sliding the window for everything else, enabling stable processing of 4 million+ tokens instead of j

Topics: attention models sink sinks tokens

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Smartwatches Recalled for Catching Fire, Burning Hands

gizmodo.com Matt Novak 2025-12-06 08:30:18

The Altafit af28 smartwatches have been recalled, according to a press release Thursday from the U.S. Consumer Product Safety Commission. The problem? The watches can overheat on their chargers and even ignite into flames. The smartwatches were sold on the Home Shopping Network from March 2025 to May 2025 for $50, marked down from $100. There have been 39 reports of the watches melting, burning, and catching fire with at least six reports of consumers’ hands being burned along with property dam

Topics: charging consumers pad smartwatch watch

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Instagram's map feature spurs user backlash over geolocation privacy concerns

cnbc.com Jonathan Vanian 2025-12-06 06:12:04

The launch of an Instagram feature that details users' geolocation data illicited backlash from social media users on Thursday. Meta debuted the Instagram Map tool on Wednesday, pitching the feature as way to "stay up-to-date with friends" by letting users share their "last active location." The tool is akin to Snapchat's Snap Map feature that lets people see where their friends are posting from. Although Meta said in a blog post that the feature's "location sharing is off unless you opt in,"

Topics: feature instagram location map said

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Over engineering my homelab so I don't pay cloud providers

news.ycombinator.com Thibault Martin 2025-12-02 15:14:15

After years of self-hosting on a VPS in a datacenter, I’ve decided to move my services at home. But instead of just porting services, I’m using this as an opportunity to migrate to a more flexible and robust set up. I will deploy services on a single mini pc. Since I need to be able to experiment and learn without disrupting my services, I will need to be able to spin up Virtual Machines (VMs). Let’s explore how I deployed Proxmox Virtual Environment on a safe host for my specific needs as a ho

Topics: ansible install network proxmox yaml

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The Paranoid Style in American Politics (1964)

news.ycombinator.com Richard Hofstadter 2025-12-06 09:55:28

It had been around a long time before the Radical Right discovered it—and its targets have ranged from “the international bankers” to Masons, Jesuits, and munitions makers. American politics has often been an arena for angry minds. In recent years we have seen angry minds at work mainly among extreme right-wingers, who have now demonstrated in the Goldwater movement how much political leverage can be got out of the animosities and passions of a small minority. But behind this I believe there is

Topics: american anti conspiracy paranoid style

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Today's NYT Mini Crossword Answers for Friday, Aug. 8

cnet.com See Full Bio 2025-12-06 09:24:00

Looking for the most recent Mini Crossword answer? Click here for today's Mini Crossword hints, as well as our daily answers and hints for The New York Times Wordle, Strands, Connections and Connections: Sports Edition puzzles. Today's Mini Crossword might make you hungry. I think I need to put a summer barbecue on my calendar now. The puzzle wasn't terribly tough, but I did mess up on 8-Across for a while, which took me some time to sort out. It was kind of fun that the first three across clue

Topics: answer answers clue crossword mini

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Vibechart

news.ycombinator.com Unknown 2025-12-06 15:36:45

vibechart To chart based on what you want to see instead of what is true, beautiful, or useful.

Topics: based beautiful chart instead true

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Apple Maps cycling directions expand to Hong Kong and Taiwan

9to5mac.com Marcus Mendes 2025-12-06 21:21:32

When Apple first launched cycling directions on Apple Maps, the feature was limited to a handful of cities like New York and Beijing. Since then, Apple has gradually expanded coverage. Now, cycling directions are also available in Hong Kong and Taiwan. If you ride a bike to get around where you live, you know that some information is essential for route planning: are there bike paths? Bike lanes? Do they cover the entire route? What is the elevation along the way? Since the limited rollout in

Topics: apple bike cycling directions hong

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Spatio-temporal indexing the Bluesky firehose

news.ycombinator.com Unknown 2025-12-06 18:32:10

Spatio-temporal indexing the BlueSky firehose Joel Gustafson / Posts / 2025-08-07 I recently added a "spatial feed" to Aurora, my map of Bluesky. Now, in addition to seeing community clusters laid out on a giant map, you can also see a real-time of posts from just the accounts currently in view. This works smoothly at all scales — you can see the most recent posts from the entire network when zoomed all the way out, and local posts from any neighborhood when zoomed in. How does this work? Th

Topics: const node post pub self

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Doximity buys Pathway Medical for $63 million to help doctors get AI-powered answers

cnbc.com Ashley Capoot 2025-12-07 02:38:49

Doximity at the New York Stock Exchange for its initial public offering on June 24, 2021. Doximity is diving deeper into artificial intelligence, announcing on Thursday the acquisition of startup Pathway Medical for $63 million. Pathway has built an AI-powered clinical reference tool that doctors can use to ask questions about guidelines, drugs and trials. Pathway's answers are synthesized from medical literature, and Doximity said the Montreal-based startup has one of the largest structured d

Topics: doctors doximity medical pathway questions

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Instacart tops estimates, issues upbeat outlook

cnbc.com Samantha Subin 2025-12-07 02:46:33

The Instacart logo is seen on a smartphone and on a PC screen. Simo, who helped take the grocery delivery company public in 2023 and guided it through a massive growth period during the Covid-19 pandemic, will step down from her position later this month as she joins OpenAI as its new head of applications. "We delivered another strong quarter, reinforcing the essential role we play in helping families save time, money, and effort putting food on the table," wrote outgoing CEO Fidji Simo in a s

Topics: billion company instacart value year

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Today's Wordle Hints, Answer and Help for Aug. 8, #1511

cnet.com See Full Bio 2025-12-07 02:00:03

Looking for the most recent Wordle answer? Click here for today's Wordle hints, as well as our daily answers and hints for The New York Times Mini Crossword, Connections, Connections: Sports Edition and Strands puzzles. Oof, today's Wordle puzzle is a pretty tough one. I know the word, but I would never just put these letters together in my guessing. I suspect a few streaks will be broken today. If you need a new starter word, check out our list of which letters show up the most in English word

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Today's NYT Connections: Sports Edition Hints and Answers for Aug. 8, #319

cnet.com See Full Bio 2025-12-07 02:00:05

Looking for the most recent regular Connections answers? Click here for today's Connections hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle and Strands puzzles. Today's Connections: Sports Edition is a real toughie.There's a fun word puzzle in the green category, and the purple one goes completely off the wall with one of those remove-and-add-a-letter twists. No fears, we'll help you through it. Read on for hints and the answers. Connections: Sports

Topics: answers connections group sports today

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Today's NYT Connections Hints, Answers and Help for Aug. 8, #789

cnet.com See Full Bio 2025-12-07 02:00:07

Looking for the most recent Connections answers? Click here for today's Connections hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle, Connections: Sports Edition and Strands puzzles. Today's NYT Connections puzzle is a fun mix of everything. You don't even want to know how long I looked for other video games after spotting Pac-Man in the grid. Waka waka... Read on for clues and today's Connections answers. The Times now has a Connections Bot, like the

Topics: answers connections group today words

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Today's NYT Strands Hints, Answers and Help for Aug. 8, #523

cnet.com See Full Bio 2025-12-07 02:00:08

Looking for the most recent Strands answer? Click here for our daily Strands hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle, Connections and Connections: Sports Edition puzzles. Today's NYT Strands puzzle assumes you have deep knowledge of a very specific musical genre. Could be tough. I knew some of the answers, but not others. If you need hints and answers, read on. I go into depth about the rules for Strands in this story. If you're looking for

Topics: answers puzzle strands today words

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Stone tools may hint at ancestors of Homo floresiensis

arstechnica.com Unknown 2025-12-07 02:32:24

Some stone tools found near a river on the Indonesian island of Sulawesi suggest that the first hominins had reached the islands by at least 1.04 million years ago. That's around the same time that the ancestors of the infamously diminutive “Hobbits” may have reached the island of Flores. Archaeologist Budianto Hakim of Indonesia’s National Research and Innovation Agency and his colleagues were the ones who recently unearthed the tools from a site on Sulawesi. Although a handful of stone flakes

Topics: hominins homo island sulawesi years

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How to use Instagram Map and set your location-sharing preferences

techcrunch.com Aisha Malik 2025-12-07 02:05:42

This week, Instagram introduced a new Snap Map-like feature called Instagram Map that lets U.S. users share their most recent active location with others and discover location-based content. If you decide to turn on your location on Instagram Map, your location only updates when you open the app or have it running in the background, meaning it doesn’t provide continuous, real-time location updates. This is different from Snap Map, which lets users choose whether their location is updated only w

Topics: feature instagram location map new

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macOS Tahoe 26 public beta 2 rolling out, here’s how to install it

9to5mac.com Marcus Mendes 2025-12-07 11:26:11

Following a distribution hiccup, Apple is now rolling out macOS Tahoe 26 public beta 2. Here’s how to install it, and what to expect. First things first: should you install the beta? You probably know the drill: Betas can be unpredictably buggy. Even if something works on one release, it is not guaranteed to work on the next. Just this week, developer beta 5 broke compatibility with the timer app I use on the menu bar, while it had been working just fine in previous betas. I’ve also been facin

Topics: 26 beta install macos public

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Adam Mosseri says 'people are confused' about how the Instagram map works

engadget.com Unknown 2025-12-07 11:47:40

Yesterday, Meta introduced a new map feature that's almost identical to Snapchat's Snap Map. The feature has quickly sparked a backlash, though, and not just because it's yet another example of Instagram ripping off a Snapchat feature. While the map requires users to opt-in to share their location, many users were surprised and alarmed to see that their Instagram map was already populated with the locations of some accounts when it launched. That's because the map automatically pulls in locatio

Topics: advertisement instagram location map tagged

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Gemini CLI GitHub Actions

news.ycombinator.com Jerop Kipruto 2025-12-07 00:28:46

In June, we launched Gemini CLI, an open-source AI agent that brings the power of Gemini to your terminal. The enthusiastic adoption from developers has been incredible. To keep up with the flood of feature requests and contributions, we put our own tool to the test — using Gemini CLI to automate issue triage and pull request reviews. When community members noticed our new workflows, they asked us to share what we’ve built. Today, we’re introducing Gemini CLI GitHub Actions. It’s a no-cost, pow

Topics: actions ai cli gemini github

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Lightweight LSAT

news.ycombinator.com Unknown 2025-12-07 10:51:59

Welcome to the lightweight LSAT The lightweight LSAT is a simple, proven, and completely free guide to the Law School Admissions Test. Who is this guide for? The lightweight LSAT is designed for students who are frustrated with their current way of approaching the LSAT. It doesn't assume you have any knowledge of the LSAT, but it will be most useful for someone who already has some experience studying. Additionally, the lightweight LSAT is written for students who are ambitious, aiming for a

Topics: lightweight lsat questions skills test

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X plans to show ads in Grok chatbot's answers

engadget.com Unknown 2025-12-07 12:00:58

Grok's responses to users on X could include paid advertisements in the future. According to the Financial Times, X owner Elon Musk told advertisers in a live discussion that his company would let marketers pay to appear in suggestions from Grok. He said that after making Grok the "smartest, most accurate AI in the world," the company is now focusing on paying "for those expensive GPUs." Musk added that if a person is asking Grok to solve a specific problem, then "advertising the specific soluti

Topics: company grok musk responses users

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2025 Porsche Panamera Turbo S: A different approach to a luxury sedan

arstechnica.com Unknown 2025-12-07 16:30:34

REIDEN, Germany—There is a lot to be said for testing a car on the roads it was developed on. A Kei car, for example, makes more sense in downtown Tokyo than on one of Nashville's arterial highways, surrounded by construction trucks. Likewise the German supersedans. For decades, an arms race has been conducted between rival engineers in Munich, Ingolstadt, Stuttgart, and Zuffenhausen, each trying to best the others and build the ultimate four-door, four-wheel Autobahn crusher, fit for the fattes

Topics: car conditions gitlin jonathan kw

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Weapons turns our deepest anxieties into a potent horror masterpiece

theverge.com Charles Pulliam-Moore 2025-12-07 16:47:19

is a reporter focusing on film, TV, and pop culture. Before The Verge, he wrote about comic books, labor, race, and more at io9 and Gizmodo for almost five years. Zach Cregger’s first major film Barbarian was tense and frightening, but it was also infused with a healthy dose of absurdity. The movie’s twisted sense of humor made it easier to stomach its grotesque violence and a bit more difficult to anticipate how its unhinged story would unfold. But Barbarian also worked surprisingly well as a

Topics: children cregger justine movie weapons

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Latest Tech News

Diabetic Man With Gene-Edited Cells Produces His Own Insulin—No Transplant Drugs Required

Trump’s Golden Dome Sparks Unprecedented Surge in Space Force Funding

OpenStore’s demise marks endgame for once-booming e-commerce aggregator market

Amtrak NextGen Acela Debuts on August 28

Royal and BlackSuit ransomware gangs hit over 450 US companies

Microsoft will kill the Lens PDF scanner app for iOS, Android

How Attention Sinks Keep Language Models Stable

Smartwatches Recalled for Catching Fire, Burning Hands

Instagram's map feature spurs user backlash over geolocation privacy concerns

Over engineering my homelab so I don't pay cloud providers

The Paranoid Style in American Politics (1964)

Today's NYT Mini Crossword Answers for Friday, Aug. 8

Vibechart

Apple Maps cycling directions expand to Hong Kong and Taiwan

Spatio-temporal indexing the Bluesky firehose

Doximity buys Pathway Medical for $63 million to help doctors get AI-powered answers

Instacart tops estimates, issues upbeat outlook

Today's Wordle Hints, Answer and Help for Aug. 8, #1511

Today's NYT Connections: Sports Edition Hints and Answers for Aug. 8, #319

Today's NYT Connections Hints, Answers and Help for Aug. 8, #789

Today's NYT Strands Hints, Answers and Help for Aug. 8, #523

Stone tools may hint at ancestors of Homo floresiensis

How to use Instagram Map and set your location-sharing preferences

macOS Tahoe 26 public beta 2 rolling out, here’s how to install it

Adam Mosseri says 'people are confused' about how the Instagram map works

Gemini CLI GitHub Actions

Lightweight LSAT

X plans to show ads in Grok chatbot's answers

2025 Porsche Panamera Turbo S: A different approach to a luxury sedan

Weapons turns our deepest anxieties into a potent horror masterpiece

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